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Design of antihistaminic transdermal films based on alginate–chitosan polyelectrolyte complexes: characterization and permeation studies
Published in Drug Development and Industrial Pharmacy, 2018
Sonia Lefnaoui, Nadji Moulai-Mostefa, Madiha M. Yahoum, Sarah N. Gasmi
Many researches have been reported on transdermal delivery systems for KF, where the effect of polymers or chemical enhancers on the skin permeation mechanism, and release kinetics were essentially investigated. In the majority of these studies, both synthetic or semi-synthetic polymers were used such as methyl methacrylate [16], poly isobutylene [17], ethyl cellulose in combination with hydroxypropyl methyl cellulose [18], Eudragit L-100, polyvinyl alcohol and Eudragit RL-100 [14], styrene-butadiene-styrene, and acrylic-rubber [19].