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Order Piccovirales
Published in Paul Pumpens, Peter Pushko, Philippe Le Mercier, Virus-Like Particles, 2022
Paul Pumpens, Peter Pushko, Philippe Le Mercier
As reviewed by Cotmore et al. (2019) concerning bocaviruses in humans, there is a significant proportion of babies that become infected with human bocavirus 1 (HBoV1) of the Primate bocaparvovirus 1 species in the early months of life, developing their own antibody responses as soon as waning maternal IgG levels render them vulnerable to infection from their environment. However, while parvoviruses can induce a broad range of pathology in humans (Qiu et al. 2017), in most people these are resulting in respiratory and gastrointestinal infections and are rarely life threatening.
Human Bocavirus
Published in Dongyou Liu, Handbook of Foodborne Diseases, 2018
José Luiz Proença-Módena, Guilherme Paier Milanez, Eurico Arruda
Human bocavirus is a member of the genus Bocaparvovirus (subfamily Parvovirinae, family Parvoviridae), which covers a group of small nonenveloped, single-stranded, mostly negative-sense DNA viruses involved in acute respiratory illness and gastrointestinal infections in humans and diarrhea and mild respiratory symptoms in cattle, but is largely asymptomatic infection in dogs.
The clinical use of parvovirus B19 assays: recent advances
Published in Expert Review of Molecular Diagnostics, 2018
Viruses adapted to the human host are found in the genera Dependoparvovirus (Adeno-Associated Viruses, AAV), Erythroparvovirus (B19V), Bocaparvovirus (HBoV1-4), Tetraparvovirus (PARV4). While AAV viruses are considered non-pathogenic and have been exploited as transduction viral vectors, the others possess a pathogenic potential that prompts for the development of diagnostic molecular testing in a clinical setting. B19V is a widely circulating virus implicated in a complex relationship with the host, and can be considered the most relevant human pathogenic virus in the family, posing the necessity of diagnostic awareness and appropriateness. The aim of this review is to present the more recent contributions to our knowledge on the course of virus infection, on its pathogenetic mechanisms, and on the appropriate molecular diagnostic methods.