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Bone Marrow Harvesting and Reinfusion
Published in Adrian P. Gee, BONE MARROW PROCESSING and PURGING, 2020
Where a normal donor is to give marrow for an allogeneic bone marrow transplant, it is common practice to remove one or two units of blood from the donor 2 or 3 weeks prior to the harvest. This autologous blood should then be refrigerated for reinfusion at the time of harvest. Problems associated with use of banked donor blood are thus avoided for normal donors. Extreme care should be taken with removal of the blood unit, and with labeling. Since autologous blood will not be subjected to any cross-matching procedure in the majority of cases, donors often sign the blood bag, which is then identified by them prior to anesthesia and reinfusion. The normal donor may then receive a course of iron and folic acid, so that hemoglobin levels have returned to their original levels prior to bone marrow donation.
Hyperthermia in oncology and nontoxic integrative treatments
Published in Clifford L. K. Pang, Kaiman Lee, Hyperthermia in Oncology, 2015
Clifford L. K. Pang, Kaiman Lee
In the process of medical ozone major autohemotherapy, the main problem is related to the storage of blood after its extraction out of the body. Any plastic bag is forbidden because medical ozone can result in the oxidation, decomposition, and damage of the plastic bag and the phthalate composition of the plastic bag can cause lesions to the body; therefore, a glass bottle or a special antioxidant blood bag must be used.
History-taking model
Published in Kaji Sritharan, Vivian A Elwell, Sachi Sivananthan, Essential OSCE Topics for Medical and Surgical Finals, 2007
Kaji Sritharan, Vivian A Elwell, Sachi Sivananthan
ProcedureWash your hands and put on a pair of gloves.Flush the IV cannula which is currently in situ with 5-10 ml of saline to check its patency.Check the patient’s surname, first name, gender, hospital number and date of birth against their identity band, drug chart and the blood compatibility report and blood unit label. These should all match.Check the patient’s blood group on the compatibility report with that on the blood bag, and if possible against the current and previous laboratory reports.Finally, with a nurse or colleague double-check the serial number of the blood unit against that on the compatibility report.Inspect the blood bag for leaks, and ensure that the expiry date has not passed.Prime (flush through) the blood-giving set with 0.9% normal saline to remove any air (never use solutions containing dextrose). Attach the blood bag and start the transfusion.Using the roller clamp, alter the drip flow rate as necessary.Commence the blood transfusion within 30 minutes of receiving the blood.Advise the patient to notify either you or one of the nursing staff if she develops a fever, joint pain, breathing difficulties, itchiness or a rash.Run approximately 25-50 ml of blood in the first 15 minutes and re-check the patient’s observations (temperature, blood pressure and heart rate). Then ask for observations to be made every 30 minutes until 1 hour after the transfusion (or as per hospital policy).Sign, date and time the drug chart and blood compatibility report.
Prevalence of G6PD deficiency in Thai blood donors, the characteristics of G6PD deficient blood, and the efficacy of fluorescent spot test to screen for G6PD deficiency in a hospital blood bank setting
Published in Hematology, 2022
Phinyada Rojphoung, Thongbai Rungroung, Usanee Siriboonrit, Sasijit Vejbaesya, Parichart Permpikul, Janejira Kittivorapart
Blood samples were obtained from 514 blood donors (401 males, 113 females) who attended the Department of Transfusion Medicine of the Faculty of Medicine Siriraj Hospital, Mahidol University, which is a national tertiary referral hospital that is located in Thailand, during December 2020 to February 2021. All included donors were eligible to donate according to the standard donor screening procedure used at our center. The mean age of donors was 33.9 ± 10.3 years (range: 18-58). After receiving approval from the Siriraj Institutional Review Board (SIRB) (COA no. R016435002), study participants were recruited and written informed consent was obtained. A whole blood donation of 450 ml was collected in either a triple blood bag system (JMS Triple Blood Bag, CPD-SAGM solution; JMS Pte Ltd., Singapore) or a quadruple blood bag system (Terumo BCT Europe, N.V., Belgium).
Factors Involved in the onset of infection following bacterially contaminated platelet transfusions
Published in Platelets, 2021
Joels Wilson-Nieuwenhuis, Mohamed El-Mohtadi, Kurtis Edwards, Kathryn Whitehead, Nina Dempsey-Hibbert
Since bacterial growth is often slowed in a biofilm, respiration, and hence CO2 production by the bacteria are reduced, which poses a problem for the automated detection systems used in the blood centers (discussed below). Indeed, it has been demonstrated that biofilm formation by the GN bacterium S. marcescens in PCs is associated with reduced bacterial detection by automated culture systems[40]. Many studies have therefore considered strategies to prevent biofilm formation in blood bags, largely focusing on modification of the material of the blood bag to reduce bacterial adherence either by physical modification[43], or chemical modification using anti-fouling polymer coatings/plasma gases[44]. However, none of these strategies, as yet, have moved into clinical use.
Strategies for improvement of blood consumption management in the operating rooms: experts´ suggestions
Published in Journal of Community Hospital Internal Medicine Perspectives, 2021
Maryam Gholami, Shima Miladi, Leila Riahi, Ali Mohammad Keshtvarz Hesam Abadi, Sezaneh Haghpanah
After that, forming a task force to investigate the reasons of blood transfusion, improving the surgeons´ skills to control bleeding, allocating a specific space in the operating room for blood bank and special refrigerators, assignment of the blood bag ordering to anesthesiologists, checking antibodies before surgeries, and correction of anemia before surgery with medication and nutrition were recommended by 8.3% for each items. Subsequently, usage of the pediatric packs in case of transfusion in children, situation analysis of any fault occurred during transfusion practice in order to resolve the problem and making others aware by organizing conferences or e-mail services, and accelerating the cross-match process and reduction the time interval between booking and preparation were determined as other important factors with frequency of 6.6% for each suggestions.