Anisochromia

Anisochromia

Peripheral Blood and Bone Marrow

Published in Harold R. Schumacher, William A. Rock, Sanford A. Stass, Handbook of Hematologic Pathology, 2019

Fermina Maria Mazzella, Gerardo Perrotta

The intensity of color in erythrocytes is extremely important, since it can be used to estimate the mean corpuscular hemoglobin concentration fairly accurately. Variation in color (anisochromia) between erythrocytes may be associated with transfused blood or sideroblastic anemia. Hypochromia, when present, should be scored 1 to 4-plus or present or increased.

Short-term oral administration of non-porous and mesoporous silica did not induce local or systemic toxicity in mice

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Journal Information

Published in Nanotoxicology, 2020

Joan Cabellos, Irene Gimeno-Benito, Julia Catalán, Hanna K. Lindberg, Gerard Vales, Elisabet Fernandez-Rosas, Radu Ghemis, Keld A. Jensen, Rambabu Atluri, Socorro Vázquez-Campos, Gemma Janer

Hematological analyses were performed using 150 µL heparinized blood in a hematology analyzer (Abacus JuniorVet, Diatron®, Budapest, Hungary). Additionally, differential leukocyte counting using Wright-Giemsa modified staining was performed by visual evaluation using optical microscopy (Leica DM100®, Wetzlar, Germany). Incidence of morphological variations in leukocytes and incidence of acanthocytes and anisochromia were also recorded.

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Peripheral Blood and Bone Marrow

Short-term oral administration of non-porous and mesoporous silica did not induce local or systemic toxicity in mice