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Vaginal or Vulvovaginal Atrophy/Atrophic Vaginitis/Genitourinary Syndrome of Menopause (GSM)
Published in Charles Theisler, Adjuvant Medical Care, 2023
Vaginal symptoms associated with menopause are common, affecting 40%–60% of postmenopausal women.1 Vulvovaginal atrophy, or atrophic vaginitis, is thinning and inflammation of the vaginal walls leading to a loss of elasticity. This leads to symptoms of uncomfortable or painful intercourse (dyspareunia), localized dryness, burning, pruritus, dysuria, and urinary incontinence. Loss of libido is also possible.
Elements of Holistic Integrative Health
Published in Carolyn Torkelson, Catherine Marienau, Beyond Menopause, 2023
Carolyn Torkelson, Catherine Marienau
Whatever your situation, if you’re reading this book, you’re likely looking to optimize your health. You may have found that conventional healthcare does not adequately address the range and types of conditions you are experiencing. You are not alone. Many postmenopausal women want comprehensive healing approaches that include nonconventional care. But where do you look for alternatives? What can you expect? Whom do you trust? And, most importantly, why even go down that path?
Fenugreek in Management of Neurological and Psychological Disorders
Published in Dilip Ghosh, Prasad Thakurdesai, Fenugreek, 2022
Rohini Pujari, Prasad Thakurdesai
Menopause is the natural stoppage of the menstrual cycle in women, occurring in their 50s, leading to the end of fertility due to a decline in ovarian follicles’ functioning. Menopause shows a rapid decrease in the blood estrogen levels (Barth, Villringer, and Sacher 2015), resulting in several neurological alterations in CNS such as depression, hot flushes, sleep disturbances, mood, and cognitive disorders (Lalo 2017). Reduction in estrogen levels during menopause is usually associated with increased oxidative stress, leading to learning and memory impairment (Borras et al. 2003; Delibasi et al. 2006). Hormone Replacement Therapy (HRT) with estrogen is considered the most effective therapy for treating postmenopausal manifestations (Doyle et al. 2009). However, severe adverse effects limit its acceptance and chronic use among postmenopausal women. Hence, there is a need for alternative therapies to treat postmenopausal cognitive deficits (Rozenberg, Vandromme, and Antoine 2013).
Decreased baroreflex sensitivity is associated with cardiometabolic risks and prehypertension status in early-postmenopausal women
Published in Clinical and Experimental Hypertension, 2021
Soundirarajan Subhashri, Pravati Pal, Gopal Krushna Pal, Dasari Papa, Nivedita Nanda
Further, SBP of 36 subjects in the early-postmenopausal group was in the prehypertensive range. As the prehypertension status in early-postmenopausal group had significant prediction by BRS as demonstrated by bivariate logistic regression (Table 5), the decreased BRS appears to be closely associated with increased BP in these postmenopausal women. In a developing country like India, where regular health checkups are not adequately available and health consciousness in general population is below standard, these postmenopausal women may remain in the state of prehypertension for few years before they clinically progress into the state of hypertension. As such, in developing counties in Indian subcontinent, the health of the women in their menopausal period is generally neglected in the society. Therefore, the findings of the present study have great socio-economic relevance as it demonstrates the considerable autonomic imbalance and CV risks in women starting from their early part of menopause. The limitations of the present study are that the sample size in each group was modest, biochemical markers of sympathetic activity have not been estimated and echocardiographic assessment of cardiac functions has not been done. Nevertheless, results of this study emphasize the provision for regular health checkups, including assessment of CV risk parameters in women in their early postmenopausal period. As it has been reported that practice of yoga improves HRV and BRS, and reduces CV risks (46), these early-postmenopausal women may be encouraged to practice yoga to reduce their cardiometabolic risks.
The effect of vulvovaginal atrophy on women’s quality of life from an Italian cohort of the EVES study
Published in Journal of Obstetrics and Gynaecology, 2020
Rossella E. Nappi, Costantino Di Carlo, Angela Maria Becorpi, Marco Gambacciani, Francesco De Seta, Raffaella Ribaldone, Chiara Benedetto, Anna Maria Paoletti
The current posthoc analysis belongs to a larger survey addressed to postmenopausal women (aged 45–75 years) attending European menopausal or gynaecological centres. Postmenopause was defined as being >12 months after the last menstrual period. In this case, we focussed analyses on the postmenopausal women in Italy that presented with at least one VVA symptom. A total of 1230 postmenopausal women were initially screened in the EVES survey in Italy (from May 2015 to March 2016). Among them, 1226 were evaluable for symptom screening and 1073 had at least one VVA symptom (women can suffer from more than one symptom). At the end, 1066 completed the global survey including QoL and sexual function questionnaires, as well as an objective gynaecological clinical examination, and were included in the current study. From the 1066 included women, a total of 926 presented with confirmed VVA by gynaecological assessment (see flow chart of the inclusion process in Supporting Information 1). All of the participants gave their written informed consent form before study entry, which was conducted in accordance with the Declaration of Helsinki and with the corresponding Institutional Ethics Committee approval.
Chilliness in Japanese middle-aged women is associated with anxiety and low n-3 fatty acid intake
Published in Climacteric, 2020
M. Terauchi, T. Odai, A. Hirose, K. Kato, N. Miyasaka
During the menopausal transition and postmenopausal periods, women are affected by a variety of symptoms, such as hot flashes, night sweats, vaginal dryness, depression, anxiety, and insomnia. Among these symptoms, chilliness, which is a feeling of cold mainly in the extremities, has been reported to be the most prevalent sexual-vasomotor symptom in middle-aged Japanese women; however, it seldom appears on the menopausal symptom checklist in North America and Europe1,2. Similar to hot flushes and night sweats, chilliness may be caused by a narrowed thermoneutral zone that is induced by estrogen deficiency3, but the underlying mechanism is not precisely known. Therefore, we aimed to determine the prevalence of chilliness in Japanese middle-aged women attending a menopause clinic and to investigate the factors associated with chilliness in this population.