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From Tracers to Treatment
Published in Alan Perkins, Life and Death Rays, 2021
Despite the introduction of iodine-enriched salt, thyroid disease remains a major health problem in some populations, particularly in the central regions of the Indian continent. Patients with an overactive thyroid have a number of miserable symptoms in addition to neck swelling. The symptoms include nervousness, anxiety, irritability twitching and trembling. Patients often have an irregular or unusually fast heart rate (palpitations), have difficulty sleeping, feel persistently weak and tired and have mood swings.
Psychological Rehabilitation of COVID-19
Published in Wenguang Xia, Xiaolin Huang, Rehabilitation from COVID-19, 2021
Ensure whether there is a hormone metabolism disorder because the abnormal physical condition is sometimes related to the psychological disorder. For example, hyperthyroidism (an overactive thyroid gland) may produce symptoms similar to generalized anxiety disorder; while hypothyroidism (an underactive thyroid gland) can produce symptoms similar to depression.
Basic medicine: physiology
Published in Roy Palmer, Diana Wetherill, Medicine for Lawyers, 2020
Situated at the front of the neck, the thyroid gland controls the level of tissue metabolism. Its principal hormone, thyroxine, is rich in iodine. If the dietary intake of iodine is low, the thyroid enlarges to trap all the available supply; the resultant swelling is called a goitre. An overactive thyroid causes an increased metabolic rate manifested by weight loss, tachycardia, and sweating. An underactive thyroid slows down many bodily functions, causing patients to gain weight and lose full mental faculties.
Sex-specific characteristics for the coexistence of asthma and COPD in the Canadian population: a cross-sectional analysis of CLSA data
Published in Journal of Asthma, 2023
Edwina Veerasingam, Zhiwei Gao, Jeremy Beach, Ambikaipakan Senthilselvan
In this study, the proportion of comorbidities in the asthma + COPD group was similar to that observed in the COPD-only group and was greater than those observed in control and asthma-only groups among both females and males. The proportion of osteoporosis was significantly greater in the asthma + COPD, COPD-only and asthma-only groups than in the control group. These finding were also reported in other studies (6,10). This association may be related to the potential confounding effect of vitamin D which has been shown to be associated with osteoporosis, asthma and COPD (35,36). In addition, systemic inflammation and glucocorticoid use have been reported to be risk factors of osteoporosis in subject with COPD (37) and long-term use of systemic glucocorticoids has been shown to be associated with osteoporosis in subjects with severe asthma (38). In this study, females had a significantly greater proportion of underactive thyroid disease than males in all the outcome groups. In a Turkish study, underactive thyroid disease was more frequent than overactive thyroid disease among subjects with COPD (39). In a large population-based study of adults aged 40 years and above from Spain, the proportion of thyroid disease and osteoporosis was greater in females than men among subjects with COPD (40). In a review article, osteoporosis has been reported to be more prevalent in females than males among subjects with COPD (41).
Recurrent thyrotoxicosis following near-total thyroidectomy
Published in Baylor University Medical Center Proceedings, 2020
Paul Gaschen, Joehassin Cordero, Alan N. Peiris
In our patient, the recurrent thyroid tissue was identified in the right thyroid bed by ultrasound and radioactive iodine scan. The match between the location of the tissue in the right thyroid bed and the tissue spared on the right side during a total thyroidectomy raises interesting questions. We believe that the right decision was to avoid injury to the recurrent laryngeal nerve by sparing a small amount of tissue in its vicinity. It remains possible that regrowth of this tissue contributed to an overactive thyroid state subsequently. Some thyroid tissue may persist after total thyroidectomies, and perhaps the term near-total thyroidectomy is a more apt description.10 The surgeon noted that a 0.5 × 0.5 × 0.5 cm piece of tissue was left in place during the surgery, and this is not an uncommon practice. Interestingly, it does not appear to take much thyroid tissue for clinical hyperthyroidism, at least in our patient. It remains to be seen whether an increasing TSI would provide an early warning of such rare recurrent thyrotoxicosis. This case also illustrates the need for ongoing long-term monitoring of patients following intervention for hyperthyroidism.