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Strategies for the diagnosis and management of meningitis in HIV-infected adults in resource limited settings
Published in Expert Opinion on Pharmacotherapy, 2021
Marise Bremer, Yakub E Kadernani, Sean Wasserman, Robert J Wilkinson, Angharad G Davis
Hyponatremia presents in 44% of TM cases, with cerebral salt wasting syndrome more frequently the underlying cause and relating to severity of the condition, than the syndrome of inappropriate secretion of antidiuretic hormone [151]. Distinction between these two causes is critical and clinical estimation of intravascular fluid volume can guide the diagnosis [152]. Fever in TBM increases 1 year mortality, but aggressive temperature control still requires further investigation [153].