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Nafcillin
Published in M. Lindsay Grayson, Sara E. Cosgrove, Suzanne M. Crowe, M. Lindsay Grayson, William Hope, James S. McCarthy, John Mills, Johan W. Mouton, David L. Paterson, Kucers’ The Use of Antibiotics, 2017
Tissue and skin necrosis can occur after accidental subcutaneous extravasation of i.v. nafcillin and phlebitis and may necessitate multiple tissue débridements and skin grafting. The exact mechanism by which nafcillin causes this is not entirely known (Le and Patel, 2014). In animals, tissue necrosis occurs after subcutaneous inoculation of nafcillin, but not with oxacillin, methicillin, and cephalothin (Tilden et al., 1980). In humans, nafcillin-induced tissue injury can be prevented by prompt administration of hyaluronidase into the site of extravasation. Other suggested treatments include cold compresses and sulfadiazine sliver cream (Zenk et al., 1981; Le et al., 2014).
Injuries of the ankle and foot
Published in Ashley W. Blom, David Warwick, Michael R. Whitehouse, Apley and Solomon’s System of Orthopaedics and Trauma, 2017
Initial treatment consists of rest, ice, compression and elevation (RICE), which is continued for 1–3 weeks depending on the severity of the injury and the response to treatment. Cold compresses should be applied for about 20 minutes every 2 hours, and after any activity that exacerbates the symptoms.
Allergic contact dermatitis of the vulva
Published in Miranda A. Farage, Howard I. Maibach, The Vulva, 2017
For pain control, non-steroidal anti-inflammatory drugs or acetaminophen should be recommended as first-line agents, as this circumvents the addition of a topical medication that may serve as an irritant or allergen. Application of cold compresses can suppress both itch and pain, but it is important to avoid excessive cold that can lead to frostbite. Though more time consuming, sitz baths may also be significantly comforting and can be utilized one to two times a day, as desired. Liberal use of topical petrolatum or zinc oxide may soothe the vulvar skin while additionally serving as a barrier to further exposures.
Pain management modalities for hidradenitis suppurativa: a patient survey
Published in Journal of Dermatological Treatment, 2022
Jennifer M. Fernandez, Alyssa M. Thompson, Mark Borgstrom, Lauren A. V. Orenstein, Jennifer L. Hsiao, Vivian Y. Shi
Overall, patients perceived the queried interventions to be only mildly to moderately effective in relieving HS pain. Cannabinoids and opioids had comparable effectiveness, and patients perceived opioids to be more effective for HS pain than NSAIDs or acetaminophen, consistent with a previous report (4). Though we found statistically significant differences in mean effectiveness ratings for various pain interventions, the absolute differences in perceived effectiveness were small and may not be clinically significant. We found a similar prevalence of marijuana usage to a prior study, but in contrast to their findings that pleasure was the most commonly reported reason for use, our cohort reported marijuana usage for pain (5). Although cold baths and compresses are commonly used by HS patients (3), warm compresses were perceived as significantly more effective than cold compresses.
Successful and quick treatment of nevus of Ota with 755nm picosecond laser in Chinese
Published in Journal of Cosmetic and Laser Therapy, 2020
Binping Luo, Liyang Kang, Jianyun Lu
All patients had their histories collected, and informed consent was obtained. Five percent compound lidocaine cream was applied topically 60 min before laser treatment. And nothing else other than topical anesthesia was used. For eye protection of these children, we usually had two or three staff keeping them stable, one staff hold children‘s head, and covered children’s eyes with gauze. A 755nm alexandrite picosecond laser (Cynosure, Westford, MA) was used in our treatment. And the laser parameter was fluence as 2.49 to 3.25 J/cm2 (3.2 and 2.8 mm spot sizes, respectively) and pulse duration as 750 picosecond. The endpoint achieved with treatment was a little whitening. Ice towels were applied to the treated area immediately for cold compress for about 30–40 min. A slight erythema and edema appeared with a remission of 2–3 days.
Treatment of facial telangiectasia with narrow-band intense pulsed light in Chinese patients
Published in Journal of Cosmetic and Laser Therapy, 2018
Huihui Gan, Baishuang Yue, Yan Wang, Zhong Lu
All the patients completed the 6-month follow-up. Eight of them had recurrence of telangiectasia. The recurrence rate was 30% (8/27), but the degree of telangiectasia was still lower than baseline. The predisposing factors of recurrence in these patients were seborrheic dermatitis (4 cases), acne (2 cases), allergic dermatitis (1 case), and high temperature in working place (1 case). According to our investigation, those patients without underlying skin disease tended to have relatively stable results after treatment. In order to lower the recurrence rate and improve the efficacy, all the underlying skin disease must be treated and kept under control in patients to be treated with DPL. The fluence must be chosen with caution in case of induction of unwanted inflammation. Sunscreen is recommmended after treatment. Cold spray or cold compress with wet gauze plus moisturization also helps maintain the result. Staying for long time under high temperature must be avoided. In our study, no relapse was observed at 1-month follow-up; the recurrence rate 3 months after treatment was 11% and 6 months after treatment was 30%. The recurrence rate at 6-month follow-up seems higher, but was not significantly different from 3-month follow-up after treatment according to the chi-square test. When there is recurrence, additional DPL treatment will be necessary.