Schamberg disease

Schamberg disease

Inflammatory Skin Diseases

Published in Aimilios Lallas, Zoe Apalla, Elizabeth Lazaridou, Dimitrios Ioannides, Theodosia Gkentsidi, Christina Fotiadou, Theocharis-Nektarios Kirtsios, Eirini Kyrmanidou, Konstantinos Lallas, Chryssoula Papageorgiou, Dermatoscopy A–Z, 2019

Aimilios Lallas, Zoe Apalla, Elizabeth Lazaridou, Dimitrios Ioannides, Theodosia Gkentsidi, Christina Fotiadou, Theocharis-Nektarios Kirtsios, Eirini Kyrmanidou, Konstantinos Lallas, Chryssoula Papageorgiou

Pigmented purpuric dermatoses represent a group of disorders that includes Schamberg disease, Majocchi purpura, eczematoid purpura of Doucas and Kapetanakis, lichen aureus, and pigmented purpuric lichenoid dermatitis of Gougerot-Blum. Round to oval, red, purpuric dots and/or globules, developing in an orange-brownish to reddish background are the dermatoscopic result of the extravasated erythrocytes and dermal deposits of hemosiderin, respectively (Figure 6.39). Linear or dotted vessels, white scales, and pigmented structures (pigmented dots/globules, network) represent frequent additional features. Similar dermatoscopic features have been described, also, in mycosis fungoides. Consequently, such lesions should be thoroughly evaluated to facilitate early diagnosis and adequate treatment.

Adverse cutaneous effects of neratinib

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Journal Information

Published in Journal of Dermatological Treatment, 2019

Ramiz N. Hamid, Christine S. Ahn, William W. Huang

The patient’s paronychia, xerosis, and acneiform rash were consistent with side effects of neratinib, while the eruption on the legs was diagnosed as Schamberg disease. For the periorificial dermatitis, she improved on a three-month course of oral doxycycline 100 mg daily. Her paronychia improved with mupirocin 2% ointment twice daily and Listerine® soaks nightly.

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Inflammatory Skin Diseases

Adverse cutaneous effects of neratinib