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Granulomatous Diseases
Published in Ayşe Serap Karadağ, Lawrence Charles Parish, Jordan V. Wang, Roxburgh's Common Skin Diseases, 2022
Albert Alhatem, Robert A. Schwartz, Muriel W. Lambert, W. Clark Lambert
Schamberg’s disease (Schamberg’s purpura; progressive pigmentary purpura) was first described by Jay Frank Schamberg (1870–1934) in 1901. Schamberg’s disease presents with discrete, nonblanchable red-brown purpuric patches (Figure 18.24). It is moderately common among middle-aged or elderly individuals and most frequently affects the legs. It is usually asymptomatic, but patients may experience mild pruritus. It takes a chronic course, with numerous exacerbations and remissions. Spontaneous resolution also may occur.
Inflammatory diseases
Published in Giuseppe Micali, Francesco Lacarrubba, Dermatoscopy in Clinical Practice, 2018
Schamberg’s disease (Figures 18.1–18.3) is characterized by usually asymptomatic, chronic, and persistent purpura and petechiae with conspicuous pigmentation located predominantly on the lower limbs. Patients with pigmented, purpuric, lichenoid dermatosis of Gougerot and Blum (Figure 18.4) develop lichenoid papules in addition to purpuric lesions, most often on the legs. Eczematoid-like purpura of Doucas and Kapetanakis (Figure 18.5) or itching purpura has many similarities to Schamberg’s disease but is generally more extensive, develops more rapidly, and is characterized by a persistent, intense itch. In Majocchi’s disease (Figure 18.6), the lesions tend to be reddish annular macules located on the lower limbs and associated with telangiectasias. Finally, lichen aureus (Figure 18.7) is a localized variant of PPD that is characterized by the appearance of sudden-onset, limited lichenoid papules in association with purpuric lesions, located commonly on the lower limbs, and occasionally on the trunk and the face.
Dermatological Mimics of Physical Abuse
Published in B. G. Brogdon, Tor Shwayder, Jamie Elifritz, Child Abuse and Its Mimics in Skin and Bone, 2012
B. G. Brogdon, Tor Shwayder, Jamie Elifritz
Schamberg’s disease is an apparently innocuous and common type of capillaritis with crops of reddish brown patches with cayenne pepper spots on the borders from hemoglobin leaked from intradermal capillaries. It is asymptomatic. Size and distribution of the lesions are quite variable. Isolated small round crops can simulate traumatic abusive lesions29,30 (Figure 5.24).
Successful treatment of Schamberg’s disease with fractional non-ablative 1540 nm erbium:glass laser
Published in Journal of Cosmetic and Laser Therapy, 2018
Yuval Hilerowicz, Eli Sprecher, Andrea Gat, Ofir Artzi
A 52-year-old man (Fitzpatrick skin type II) presented with a 15-year history of Schamberg’s disease on his lower legs. He had not undergone any earlier treatment for the condition. Clinical examination showed non-bleaching reticulate brown macules over the anterior aspect of the lower legs (Figure 1(a)). There was a history of mild diabetes mellitus in the patient for which he was currently not on any medications including blood thinners. Histological examination of a pretreatment biopsy demonstrated mild lichenoid lymphocytic infiltrate with hemosiderin pigment (Figure 2(a)), highlighted by ferrum stain in the upper dermis (Figure 3(a)).