China
Africa
Explore chapters and articles related to this topic
Dermoscopy in General Dermatology
Published in Ashfaq A Marghoob, Ralph Braun, Natalia Jaimes, Atlas of Dermoscopy, 2023
Iris Zalaudek, Nicola di Meo, Paola Corneli
Cutaneous warts are due to human papillomavirus. On close examination, one can appreciate disruption of dermatoglyphics or skin marking, as well as thrombosed capillaries. Warts can sometimes be difficult to distinguish from other cutaneous lesions, such as callus, corn, or even melanoma.6 Under dermoscopy, verruca vulgaris displays a mosaic pattern, defined as “multiple densely packed papilla, each containing a central red or black dot or loop, which is surrounded by a whitish halo”7,8 (Figure 12a.2 a, b). The red and black dots and loops represent normal and thrombosed capillaries, respectively. Plantar warts show verrucous, yellowish, structureless areas with an irregular distribution of black dots or streaks corresponding to thrombosed vessels and microhemorrhages due to pressure effects on the sole. In contrast, calluses demonstrate homogeneous opacities, and corns exhibit a translucent central core.9
Retinoids in Other Skin Diseases
Published in Ayse Serap Karadag, Berna Aksoy, Lawrence Charles Parish, Retinoids in Dermatology, 2019
Uwe Wollina, Piotr Brzezinski, André Koch
Verrucae vulgaris (VV) (common warts) are caused by the human papilloma virus (HPV), mainly HPV-1 and -2, less common HPV-4 to -7. Although VV are common, the ideal treatment has yet to be developed. Widespread warts are a particular challenge. In such cases, oral acitretin is a therapeutic option (67–69). A dosage of 25 mg to 30 mg/day achieved a complete response of widespread recalcitrant common warts within 3−6 months of treatment (68,69). In two adult patients with multiple plane warts of skin and mucosa, 0.3−0.4 mg/kg isotretinoin achieved a complete remission after 1 month (70). There is one randomized comparative open trial for plantar warts with either topical adapalene or cryotherapy. This study enrolled 50 patients with 424 plantar warts. Adapalene gel 0.1% was used twice daily under occlusion. All warts cleared on average within 36.1 days with adapalene compared to 52.2 days with cryotherapy (71).
Skin infections
Published in Ronald Marks, Richard Motley, Common Skin Diseases, 2019
Plantar warts are painful, some warts are irritating, and all warts are unsightly and aggravating. They are a particular problem in immunosuppressed patients. In one congenital condition, plane warts spread extensively on the arms, face, trunk and limbs and some lesions can transform to squamous cell carcinoma. This rare disorder, known as epidermodysplasia verruciformis, seems to have its basis in a disorder of delayed hypersensitivity.
Our experience using 1064 nm Nd:YAG in palmoplantar warts
Published in Journal of Cosmetic and Laser Therapy, 2022
Hai Thi Thu Le, Cuong Truong Van, Minh Nguyen Thi, Firas Al-Niaimi
Cutaneous warts are benign lesions that occur in the mucosa and skin caused by the human papillomavirus (HPV) and are one of the commonly seen benign cutaneous tumors in daily medical practice. At present, over 100 subtypes of HPV have been identified. The primary manifestations of HPV infection include common warts, genital warts, flat warts, palmoplantar warts, focal epithelial hyperplasia, epidermodysplasia verruciformis, and plantar cysts. Palmoplantar warts are typically caused by HPV subtype 1 (most common) followed by subtypes 2, 3, 4, 27, and 57, occurring in both males and females of various ages (1). Prevalence is highest in school-aged children, students, and manual laborers and may be transmitted by direct or indirect contact. In general, the lesions are asymptomatic, with the occasional pain experienced with the application of pressure. Warts can spontaneously disappear without treatment. In children, about half resolve within a year, and about two-thirds disappear within 2 years. It may take longer for warts to clear up for adults, with 5–10 years reported in some patients (2). Plantar warts are frequently symptomatic with pressure pain and can have an adverse effect on the quality of life (3, 4). The painful and uncomfortable feeling associated with plantar warts in particular during prolonged walking and standing is often a reason for seeking treatment.
Diagnostic techniques in HPV infections and the need to implement them in plantar lesions: A systematic review
Published in Expert Review of Molecular Diagnostics, 2021
Alberto Aldana-Caballero, Felix Marcos-Tejedor, Raquel Mayordomo
Plantar warts are HPV lesions found in the skin of the foot, and our results identified a noticeable lack of research about their diagnosis. Visual inspection, whether direct or indirect with the aid of devices, appears to be the most common approach among health professionals and podiatrists. Similarly, cellular changes visualized in microscopy cannot differentiate between HPV infection and other skin conditions commonly found in plantar epidermis [67], and therefore no reliable diagnostic method is currently available. We encourage researchers to address the vast possibilities in diagnostic techniques for plantar lesions, and podiatrists and other health professionals should be aware of such research to implement the techniques in the clinical setting. One of the limitations of the diagnostic techniques for plantar warts identified in this study is that they are first attempts and require further research and larger sample sizes and, above all, they need to be compared with other techniques or a gold standard to validate the method studied.
Combined therapy of plantar warts with topical bleomycin and microneedling: a comparative controlled study
Published in Journal of Dermatological Treatment, 2020
Hend D. Gamil, Mohamed M. Nasr, Fathia M. Khattab, Amira M. Ibrahim
Plantar wart (Verruca plantaris) is a wart occurring on the sole or toes of the foot. Plantar warts can be painful due to their callused, endophytic papules that have deeply penetrating sloping sides and a central depression (1). The types of human papillomavirus (HPV) that have been isolated from plantar warts include HPV-1, -2, -3, -4, -27, -29, -57, -60, -63, -65, -66, and -69. In one randomized controlled trial, 88% of plantar warts were caused by HPV-1, -2, -27, or -57. Most plantar warts are attributed to HPV-1 (2). Plantar warts exhibit an annual incidence of 14% in the general population. Transmission of warts occurs from direct person to person contact or indirectly by fomites (3). Treatment of plantar warts is a therapeutic challenge regarding both tolerability and efficacy. An innovative approach of combining microneedling with topical bleomycin for the treatment of recalcitrant plantar warts was first reported by Konicke and Olasz (4).