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Pathology of Breast Cancer
Published in Raymond Taillefer, Iraj Khalkhali, Alan D. Waxman, Hans J. Biersack, Radionuclide Imaging of the Breast, 2021
The diagnosis of mucinous carcinoma in FNAB and core biopsy is usually not difficult. The clinical information on the age of the patient can easily exclude the possibility of mucocele as a differential diagnosis [25]. However, in the presence of a mixed mucinous carcinoma, FNAB or core biopsy can potentially miss the infiltrating component. This is prognostically important, since mixed forms of mucinous carcinoma behave the same as an infiltrating duct cell carcinoma [107]. Therefore, it may be necessary to perform a surgical biopsy to assess the patient prognosis on evaluation of the entire lesion.
The breasts
Published in C. Simon Herrington, Muir's Textbook of Pathology, 2020
Mucinous carcinoma comprises approximately 1% of invasive carcinomas. They are formed from clumps of moderately sized epithelial cells lying within lakes and pools of mucin. Numerous other rare patterns of invasive carcinoma may be seen (all <1% of the total) including invasive papillary carcinoma, invasive micropapillary carcinoma, metaplastic carcinoma (spindled cell, squamous or matrix producing, or a combination) and very rare salivary gland-type cancers, such as adenoid cystic carcinoma, and secretory carcinomas. Combinations of histological forms of invasive breast cancer, such as mixed mucinous and NST carcinoma or mixed lobular and NST carcinoma, are quite common and are classified as being of mixed type when the lesion is less than 90% ‘pure’ in type.
Breast
Published in Joseph Kovi, Hung Dinh Duong, Frozen Section In Surgical Pathology: An Atlas, 2019
Joseph Kovi, M.D. Hung Dinh Duong
Mucinous carcinoma is a cancer of the breast with a relatively favorable prognosis. Mucinous carcinoma must be clearly differentiated from the rare signet-ring cell carcinoma of the mammary gland which has an extremely poor prognosis (Figures 67 and 68).82
Leukemia Inhibitory Factor Impairs the Function of Peripheral γδT Cells in Patients with Colorectal Cancer
Published in Immunological Investigations, 2023
Xueyan Xi, Ting Deng, Fen Qiu, Yunhe Zhu, Yumei Li, Gang Li, Yang Guo, Boyu Du
Patients with CRC were recruited from Renmin and Taihe Hospitals in Shiyan City between April 2020 and October 2022. All patients were newly diagnosed with CRC and had not previously received treatment. Sex- and age-matched healthy participants were also recruited from the same hospitals. No infections or other oncological diseases were found in any participant. The mean ages of the patients and healthy subjects were 56.8 and 45.2 years, respectively. A small number of CRC patients and healthy donors had diabetes, heart disease, and hypertension. According to the tumor, node and metastasis (TNM) stage, the patients were divided into groups I, II, III, and IV. According to pathological characteristics, the patients were divided into adenocarcinoma and mucinous carcinoma groups. Detailed information on the recruited patients and healthy participants is shown in Table 1. This study was approved by the Clinical Ethics Committee of the Hubei University of Medicine (2020-TH-017). All individuals had provided informed consent to participate in this study.
Effect of comorbidity assessed by the Charlson Comorbidity Index on the length of stay, costs, and mortality among colorectal cancer patients undergoing colorectal surgery
Published in Current Medical Research and Opinion, 2023
Xuexue Zhang, Xujie Wang, Miaoran Wang, Jiyu Gu, Huijun Guo, Yufei Yang, Jian Liu, Qiuyan Li
Control variables included age, gender, type of insurance, hospital category, surgery type, and histological type of colorectal cancer. The type of insurance included urban employee basic medical insurance for employed workers, urban resident basic medical insurance for urban residents without a stable job, a new cooperative medical system for rural residents, and others. Different insurance varies in terms of payment methods, reimbursement proportion, and coverage26. The hospital category comprised Chinese medicine hospitals, western medical hospitals, integrated traditional Chinese and Western medicine hospitals, and tumor hospitals in China, while they had different characteristics concerning treatment features and hospitalization costs. The histological type was categorized into adenocarcinoma, mucinous carcinoma, signet-ring cell carcinoma, and others.
Endocrine mucin-producing sweat gland carcinoma: a systematic review and meta-analysis
Published in Journal of Dermatological Treatment, 2022
Michael H. Froehlich, Keith R. Conti, Ivy I. Norris, Jordan J. Allensworth, Nicole A. Ufkes, Shaun A. Nguyen, Evelyn T. Bruner, Joel Cook, Terry A. Day
The results demonstrated that 41.6% of lesions evaluated had co-existent IMC, the histologic pattern seen in PCMC. Zembowicz et al. reported 12 cases of EMPSGC, of which 50% also had components of IMC. The authors suggested that EMPSGC likely has the capacity to progress from an in-situ tumor with minimal mucous production, to an invasive carcinoma, PCMC, with cells suspended in pools of mucin (2). This observation led many to believe that EMPSGC and PCMC exist along a progressive spectrum of disease. EMPSGC is histologically analogous to solid papillary carcinoma, a well-established precursor to mucinous carcinoma of the breast. Therefore, just as solid papillary carcinoma of the breast progresses into a mucinous carcinoma, it is suggested that EMPSGC may behave in the same manner by progressing to PCMC (1,35).