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Use of Dermatologics during Pregnancy
Published in “Bert” Bertis Britt Little, Drugs and Pregnancy, 2022
The etiology of erythema multiforme, another dermatitis, is virtually unknown. Erythema multiforme is characterized by erythematous “target lesions.” An increased frequency of outbreaks occurs during pregnancy among women with erythema multiforme. The condition can be treated with antihistamines during pregnancy. If antihistamines are not sufficient, steroids may be effective in some cases. Triamcinolone should not be used during pregnancy.
Gastroenterology
Published in Anna Kowalewski, SBAs and EMQs in Surgery for Medical Students, 2021
Erythema multiforme is an acute, self- limiting hypersensitivity skin reaction caused by infections and medications. The lesions are described as target lesions. Target lesions are circular with a central blister. In Crohn’s disease, the patient is most likely to suffer from erythema nodosum, which is an inflammation of the fat under the skin (panniculitis). It manifests itself as red nodules, most often over the patient’s shins.
Bufexamac
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
In a period of 1.5 year in 1991-1992, at a University clinic in Germany, 4 patients (3 women, 1 man, ages 28,29,34, and 62 years) were investigated who had developed an erythema multiforme-like reaction with urticarial papules and plaques following acute contact dermatitis from 2 different bufexamac-containing topical preparations. Bufexamac had been applied to discrete erythema (n=3) or circumscribed atopic dermatitis, and allergic contact dermatitis appeared after a few days to 3 weeks. Histologically, the lesions did not show changes typical of erythema multiforme. Patch tests were positive to bufexamac 5% in all 4, to 1% pet. in 2 and all 4 also reacted to their own bufexamac ointment/cream. The authors suggest that a systemic allergic reaction with spreading of the lesions may have occurred from percutaneous absorption of the allergen (26).
Erythema multiforme following exposure to the herbicide atrazine
Published in Baylor University Medical Center Proceedings, 2021
Madeline Frizzell, Nhan M. Nguyen, Sonal A. Parikh, Maya Sinai, Leonard Goldberg
Erythema multiforme is an acute, self-limiting, inflammatory skin eruption with many known causes, most commonly infectious agents and drugs. Less common causes include malignancy, environmental factors, autoimmune disease, and vaccinations.1 There have been a few reports of erythema multiforme resulting from exposure to the herbicides paraquat, glycophosphate, alachlor, and butachlor, but no reports discussing an erythema multiforme reaction to the herbicide atrazine.2–5 We present a case of erythema multiforme caused by atrazine, or 1-chloro-3-ethylamino-5-isopropylamino-2,4,6-triazine.
Cushings syndrome complicating pemphigoid gestationis
Published in Cogent Medicine, 2018
O.Y. Olisova, N.P. Tepljuk, A.R. Hubail, R.K. Belkharoeva, O.V. Grabovskaya, V.B. Pinegin
In the beginning of March 2017, the time when she presented to our practice, the differential diagnosis we had in mind was bullous pemphigoid, Duhring dermatitis, and erythema multiform. Based on the clinical presentation, as well as on results of the histologic examination and of the indirect immunofluorescence test (IIFT) the patient was given the diagnosis of erythema multiforme. She was administered Dapson 100 mg a day and Prednisolone was reduced by 5 mg a week. The patient was hospitalized for further examination and management.
Erythema multiforme after third COVID-19 vaccination (Pfizer-BioNTech)
Published in Baylor University Medical Center Proceedings, 2022
Sonali Batta, Austinn C. Miller, Susuana Adjei, Laurie A. Temiz, Stephen K. Tyring
Erythema multiforme (EM) may occur in the setting of recent COVID-19 infection or vaccination. Timely recognition and treatment are necessary to exclude other potential causes of EM and prevent worsening of skin and mucous membrane involvement.