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Diaper Rash/Diaper Dermatitis/Contact Dermatitis
Published in Charles Theisler, Adjuvant Medical Care, 2023
Diaper rash is marked by red, irritated, or tender-looking skin in the diaper region (i.e., buttocks, thighs, and genitals). It results from contact with urine and feces that inflames the skin and breaks down outer skin layers. Another contributing factor to diaper dermatitis is Candida albicans. Diaper dermatitis can cause diffuse reddening of the skin with papules, vesicles, edema, and scaling of the involved areas as well as psoriasiform lesions, secondary erosions, and ulcerations.1
Flexures
Published in Richard Ashton, Barbara Leppard, Differential Diagnosis in Dermatology, 2021
Richard Ashton, Barbara Leppard
The common type of nappy/diaper rash is an irritant reaction to urine and faeces held next to the skin under occlusion. Bacteria in the faeces break down urea in the urine into ammonia, which is very irritant to the skin. Clinically, the rash is patchy and tends to involve the convex skin in contact with the nappy (buttocks, genitalia, thighs) rather than the skin in the folds (Fig. 10.13). In mild cases there is just erythema, but when severe, erosions or even ulcers can develop. The affected area is sore and cleaning or bathing the area produces a lot of discomfort.
Superficial mycoses in the elderly
Published in Robert A. Norman, Geriatric Dermatology, 2020
B. P. Glick, M. Zaiac, G. Rebell, N. Zaias
Ordinary cutaneous candidiasis consists of localized, approximately 1 mm diameter, pustules on erythematous bases, which coalesce to form more widespread erythema and erosions of the stratum corneum and superficial epidermis. Cutaneous candidiasis occurs in moist and intertriginous areas, under conditions of increased temperature and sweating22. A classic form is diaper rash in children.
Clinical Profile and Outcomes of Primary Immunodeficiency and Malignancy in Childhood at a Tertiary Oncology Center in Developing Country
Published in Pediatric Hematology and Oncology, 2022
Derya Özyörük, Zeliha Güzelküçük, Ayse Metin, Suna Emir, Arzu Yazal Erdem, Dilek Kacar, Ayca Koca Yozgat, Can Baris Aker, Selma Çakmakçı, Sonay Incesoy Özdemir, Neriman Sari, Meriç Kaymak Cihan, Namık Yasar Özbek, İnci Ergürhan İlhan
All patients (early and late periods) who received chemotherapy experienced with various degree neutropenia (Grade 3/4) and infections. They also experienced moderate to severe mucositis (Grade 2/3/4) and mild hepatotoxicity (grade 1/2) due to treatment. One patient had a seizure after developing inappropriate antidiuretic hormone (ADH) syndrome. One patient had developed toxoplasmosis during remission period. One patient developed Coombs positive autoimmune hemolytic anemia. One patient had chylothorax. One patient experienced recurrent herpes zoster infections and chronic active EBV infection at CSF/blood. Two other patients also had chronic active EBV infection. One patient developed severe heart failure. Two patients had polyneuropathy due to vincristine. The patient with MPO deficiency developed severe diaper rash due to candida.
Assessment of antifungal efficacy of itraconazole loaded aspasomal cream: comparative clinical study
Published in Drug Delivery, 2022
Caroline Lamie, Enas Elmowafy, Maha H. Ragaie, Dalia A. Attia, Nahed D. Mortada
All parents were advised to care about diaper rash with respect to more frequent changing of the diapers, prompt removal of dirty or wet diapers and gentle washing of the buttocks after each change. Each patient received a container of the used formula, and the caretakers were guided to apply the formula with the fingertips to the involved areas at diaper changes two times daily for a total of 10 days. After the designated treatment period, the patients were subjected to clinical examination and dermoscopic reassessments and skin scrapings.
Evaluation of Cholestyramine 15% Ointment in Relieving Pruritus and Burning After Ileostomy: A Rrandomized, Double-Blind Placebo-Controlled Clinical Trial
Published in Journal of Investigative Surgery, 2020
Shahram Ala, Mina Alvandipour, Majid Saeedi, Sarvenaz Seyedein, Mahila Monajati, Neda Koulaeinejad
In another study, the efficacy of cholestyramine (5%) ointment was evaluated on a neonate with a painful and severe diaper rash, which was refractory to other treatments. The ointment was applied after each defecation. After 2 days, a remarkable recovery was observed, and the rash was completely resolved the following week [25].