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Anogenital region
Published in Robin Lewallen, Adele Clark, Steven R. Feldman, Clinical Handbook of Contact Dermatitis, 2014
Monica Huynh, Michael P. Sheehan, Michael Chung, Matthew Zirwas, Steven R. Feldman
Diaper dermatitis affects the area covered by the diaper and is most often irritant in nature. A secondary infection with candida should also be considered. A clue to ACD secondary to diaper components is an eczematous dermatitis that spares the skinfolds and is refractory to conventional therapies for diaper dermatitis. Allergens to consider in this setting include fragrances utilized to provide a pleasant odor to the diaper, coloring dyes, glues, and rubber-related allergens; it is also important to consider wet wipes, which are often used during the diaper-changing process.5,6,7 If the pattern of dermatitis favors the hips and lateral buttock, rubber accelerators such as mercaptobenzothiazole should be considered. This pattern has been referred to as the “Lucky Luke” dermatitis and is a subset of allergic contact diaper dermatitis in which the child is reacting to the elastic bands found in disposable diapers.8,9
Assessment of antifungal efficacy of itraconazole loaded aspasomal cream: comparative clinical study
Published in Drug Delivery, 2022
Caroline Lamie, Enas Elmowafy, Maha H. Ragaie, Dalia A. Attia, Nahed D. Mortada
Amid the rising skin illnesses, superficial fungal infections are the most frequently encountered dermal ailments such as candidiasis and tinea. Candida albicans is a normal commensal yeast of human microflora which is found mainly on the surface of mucosal membranes like gastrointestinal, respiratory, and genitourinary tracts. It is a major species that are responsible for 46.3% of candidiasis infection (Pedrosa et al., 2014). Diaper dermatitis is a main reason for candidiasis infection due to direct contamination of stool containing CA with inflamed skin from diapers. The infant defense response and the how deep the inflammation affect the integrity of SC are critical factors that determine whether candida can stay in SC or reach the deeper layers (Spraker et al., 2006). TC and TVC are two types of fungal infections that affect mainly the superficial dermal strata and present in the trunk and extremities (Dadar et al., 2018). In tropical climates especially in places characterized by poverty and inadequate hygiene, TC and TVC are widespread in teenagers and young adults.
Complementary and alternative treatment methods practiced by parents in pediatric cases diagnosed with atopic dermatitis
Published in Journal of Dermatological Treatment, 2022
Ayşe Akbaş, Zeynep Şengül Emeksiz, Ahu Yorulmaz, Yıldız Hayran, Fadime Kılınç, Halil Ibrahim Yakut, Müge Toyran, Kezban İpek Demir
The patients’ AD diagnosis time was 5.5 months (IQR: 4–12 months) and median follow-up time was 2 months (IQR: 2–10.5). While the number of admissions to the hospital due to AD ranged from 1 to 4 in 68.8% of the patients, it was five or more in 31.2% of the patients. AD was mild in 25.4%, moderate in 50.8%, and severe in 23.8% of the patients. The median SCORAD was calculated as 25 (IQR: 15–38.8). While AD was accompanied by seborrheic dermatitis in 19.5% of the patients, diaper dermatitis was present in 6.1%. 93.5% of the patients were using a moisturizer. 49.4% of the patients were using one type of moisturizer, 19.5% of them were using two types of moisturizers, and 24.7% were using three or more different types of moisturizers. The localization of the lesions was in the head and neck region in 66.3%, in the extremities in 14.5%, in the head-neck and extremities in 10.8%, in the trunk in 3.6% and in the whole body in 3.6%.