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Bacterial Infections of the Oral Cavity
Published in K. Balamurugan, U. Prithika, Pocket Guide to Bacterial Infections, 2019
P. S. Manoharan, Praveen Rajesh
Bleeding upon slightest provocation along with clinical signs and symptoms of surface color and texture absence of stippling will denote reactive inflammation. Breakdown of junctional epithelium and deepening of sulcus is known as a periodontal pocket, which is measured using a probing instrument such as a William’s periodontal probe or Community Periodontal Index for Treatment Needs (CPITN) probe, which has got a blunt end. Bone loss can be appreciated with radiographs (i.e., orthopantomography or intra-oral periapical).
The heart in hypertension
Published in H. Gavras, The Year in Hypertension 2004, 2004
EDWARD D FROHLICH, HECTOR O VENTURA
The study featured above evaluates the relationship between periodontal disease and LV mass in 104 patients with essential hypertension who had echocardiographic studies to evaluate LV mass and assessment of periodontal status according to the community periodontal index of treatment needs (CPITN). With increasing severity of periodontitis there was a progressive increase in systolic pressure and LV mass. In addition, LV mass was the only determinant of severe periodontal disease (Table 2.11; Figs. 2.13, 2.14). The underlying mechanisms by which this association occurs remain speculative and were not evaluated in this study. One point not at all considered is that patients with essential hypertension with LVH must have pressures of higher stages and, hence, may have received calcium antagonists in their past. As is generally known, this class of drugs, especially the dihydropyridines, have as their most common side effect the development of gingival hyperplasia. The clinical importance of the study is related to the suggestion that periodontal diseases can provide an easily accessible biological assay for more accurate definition of cardiovascular risk assessment in patients with hypertension.
Detection of polyomavirus microRNA-5p expression in saliva shortly after kidney transplantation
Published in Journal of Oral Microbiology, 2021
Ana Carolina Mamana, Maria Stincarelli, Dmitry José De Santana Sarmento, Alexandre Mendes Batista, Tânia Regina Tozetto-Mendoza, Marina Gallottini, José Osmar Medina De Abreu Pestana, Paulo Henrique Braz-Silva, Simone Giannecchini
This is a cohort study conducted in a renal transplant unit of the Federal University of São Paulo Kidney and Hypertension Hospital, São Paulo, Brazil. Patients older than 18 years who underwent single kidney transplantation were initially included. Exclusion criteria were kidney transplants associated with another organ, immunosuppressive therapy before initiation of the study, and HIV positivity. This study was approved by the Research Ethics Committees of the Kidney and Hypertension Hospital and of the Osvaldo Ramos Foundation, according to protocol number 2,362,239, and by the University of São Paulo School of Dentistry, according to protocol number 1,824,857, following the ethical standards set by the Declaration of Helsinki. All the participants signed a free informed consent form before being examined in two different periods, always by the same examiner, as follows: the first examination within 24 hours before renal transplantation and the second 60 days after the surgery. All clinical data in the patients’ charts, including laboratory test values, were assessed. For intraoral examination, the same experienced dentist used the decayed, missing and filled teeth index (DTMF) and community periodontal index of treatment needs (CPITN). Collection of saliva and blood samples was also performed for molecular analysis. Whole saliva samples were obtained without previous stimulation, that is, by asking the patient to spit into a sterile container. Blood samples were collected at the same moment as the saliva collection. After collection and identification, the blood and saliva samples were centrifuged at 800 rpm in a conical tube, and then 500 μL aliquots of the supernatant of each sample obtained after centrifugation were placed into cryotubes for storage in a freezer at −80°C until laboratory analysis.
Longitudinal study on oral shedding of human betaherpesviruses 6 and 7 in renal transplant recipients reveals active replication
Published in Journal of Oral Microbiology, 2020
Jéssica Vasques Raposo, Dmitry José De Santana Sarmento, Rafaela Barbosa Da Silva Pinto, Amanda Oliveira Lopes, Marina Gallottini, Tânia Regina Tozetto-Mendoza, Paulo Henrique Braz-Silva, Vanessa Salete de Paula
The periodontal condition was evaluated by Community Periodontal Index of Treatment Needs (CPITN). Scoring and treatment criteria were defined as follows: 0 = healthy periodontium, 1 = gingival bleeding during probing, 2 = dental calculus, 3 = periodontal pockets (with interproximal attachment loss) 3–5 mm, 4 = periodontal pockets of 6 mm depth [17]. The mean score value was used for statistical analysis.