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Heavy Metal Pollution and Medicinal Plants
Published in Azamal Husen, Environmental Pollution and Medicinal Plants, 2022
Allah Ditta, Naseer Ullah, Xiaomin Li, Ghulam Sarwar Soomro, Muhammad Imtiaz, Sajid Mehmood, Amin Ullah Jan, Muhammad Shahid Rizwan, Muhammad Rizwan, Iftikhar Ahmad
Shen et al. (2020) reported a strong association among Zn, Fe, Mg, and Cu uptake and translocation processes between soil to plants, which was confirmed through strong elemental correlations among the atomic radii of the fundamental elements Zn, Fe, Mg, and Cu, due to the similarities among their atomic radii as well as octahedral configuration. Zhou et al. (2020) studied the variation in the concentration of amino acid, malondialdehyde (MDA), and antioxidant enzymes in the fine leaves of the Schizonepeta herb, thyme, and catnip exposed to Pb and Cd stress. The results showed that concentrations of HMs and species of plants were correlated to the overall amount of amino acids synthesized by the root system as well as the amount of each amino acid. Monochoria hastata plants were subjected to Cd stress in another experiment. The plants displayed some signs of noticeable toxicity like leaf fall, withering, and chlorosis when the Cd level was 15 mg L-1 (Baruah et al., 2016). Similarly, (Brima, 2017) reported that, among everything in the medicinal plants, Cd occurred at the minimum amounts while Vitex agnus-castus displayed such features at the maximum concentration and the concentrations of Cd ranged from 0.01 to 0.10 mg kg-1.
AN ORTHODOX PRACTITIONER'S VIEW OF CHINESE MEDICINE
Published in Kevin Chan, Henry Lee, The Way Forward for Chinese Medicine, 2001
We were able provisionally to identify the plants in the prescription as: Ledebouriella seseloides, Potentilla chinensis, Clematis armandii, Rehmannia glutinosa, Paeonia lactiflora, Lophatherum gracile, Dictamnus dasycarpus, Tribulus terrestris, Glycyrrhiza uralensis and Schizonepeta tenuifolia.
Novel carbon dots derived from Schizonepetae Herba Carbonisata and investigation of their haemostatic efficacy
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2018
Meiling Zhang, Yan Zhao, Jinjun Cheng, Xiaoman Liu, Yongzhi Wang, Xin Yan, Yue Zhang, Fang Lu, Qingguo Wang, Huihua Qu
Schizonepetae Herba (Jingjie), the dried aerial parts of the plant Schizonepeta tenuifolia (Benth.) Briq. (family Labiatae), is a kind of medicinal herb widely used in China, Korea and Japan [1]. The charcoal-processed product of Schizonepetae Herba (SH), SH Carbonisata (SHC), has been widely used to treat haemorrhagic conditions for more than 1000 years in TCM and was recorded in the Prescriptions People's Welfare Pharmacy during the Song Dynasty (960–1279 A.D. in China) at the earliest. Moreover, evidence from modern pharmacological studies and considerable clinical data have also demonstrated its significant efficacy in the treatment of numerous kinds of haemorrhage such as haematochezia, metrorrhagia, metrostaxis and postpartum haemorrhage [2]. Furthermore, SHC was acknowledged in the PPRC (2015) as a haemostatic drug. Tremendous efforts have been made to elucidate the material basis of SHC and other charcoal drugs from the perspective of active small molecule compounds, but the results have been unsatisfactory. This predicament and challenge compelled us to focus on the novel substances generated after charcoal processing, which are carbon dots (CDs).
Haemostatic bioactivity of novel Schizonepetae Spica Carbonisata-derived carbon dots via platelet counts elevation
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2018
Ziwei Sun, Fang Lu, Jinjun Cheng, Meiling Zhang, Yue Zhang, Wei Xiong, Yan Zhao, Huihua Qu
Schizonepetae Spica (SS), namely Jing Jie Sui in Chinese, is the desiccative spica of Schizonepeta tenuifolia Briq. (ST), which belongs to the family Lamiaceae. In the Ming Dynasty, Schizonepetae Spica Carbonisata (SSC), the charcoal processed product of SS, was first documented in Compendium of Materia Medica (1552–1578 A.D.) for the treatment of haemorrhagic conditions. SSC has been widely used in treating haemorrhagic conditions with pronounced effects for hundreds of years and acknowledged in the 2015 Pharmacopoeia of the People’s Republic of China (PPRC) as a haemostatic charcoal drug.
Pulegone inhibits inflammation via suppression of NLRP3 inflammasome and reducing cytokine production in mice
Published in Immunopharmacology and Immunotoxicology, 2019
Qingxin Yang, Jie Luo, Hongjun Lv, Taoqun Wen, Boyu Shi, Xiaobo Liu, Nan Zeng
Pulegone, a key compound in Schizonepeta essential oil, has been identified as a component of the anti-inflammatory action [20]. It exerts an array of pharmacology functions, including anti-inflammatory, anti-oxidant, anti-biotic, and anti-ulcer effects [21]. However, its underlying molecular mechanisms on NLRP3 inflammasome still remain equivocal [21,22]. Here, we aimed to explore the effects of pulegone on LPS-induced C57BL/6J mice sepsis model and its modulatory effect on NLRP3 inflammasome.