China
Africa
Explore chapters and articles related to this topic
Ethnobotany of the Silk Road – Georgia, the Cradle of Wine
Published in Raymond Cooper, Jeffrey John Deakin, Natural Products of Silk Road Plants, 2020
Rainer W. Bussmann, Narel Y. Paniagua Zambrana, Shalva Sikharulidze, Zaal Kikvidze, David Kikodze, David Tchelidze, Ketevan Batsatsashvili
Given reports of the toxicity of Rhododendron sp., which extend from ancient Greek and Chinese sources to the present day, use of the species as agent to clear beer and as medicinal tea is rather surprising (Bussmann et al., 2016a). Careful use of certain species has also been reported for food and medicine.
Grayanotoxins
Published in Dongyou Liu, Handbook of Foodborne Diseases, 2018
Grayanotoxins are naturally occurring compounds that may be found exclusively in the family Ericaceae plants, including Kalmia latifolia, Pieris spp., and Rhododendron spp. They may also be found in secondary sources such as honey (also known as mad honey) produced from Rhododendron plants.
Investigation of genotoxic effects of rhododendron honey using three mammalian bioassays in vivo
Published in Drug and Chemical Toxicology, 2022
Pinar Goc Rasgele, Fulya Dilek Gokalp, Salih Tunc Kaya, Meral Kekecoglu, Merve Kambur Acar
Rhododendron honey known as ‘crazy honey,’ ‘bitter honey’ or ‘mad honey’ among local people was obtained from rhododendron species belonging to Ericaceae family. Frequently seen toxic rhododendrons in Turkey are R. luteum and R. ponticum. Anti-inflammatory (Rylski et al. 1979, Erdemoglu et al. 2003), anti-microbial (Usta et al. 2012), anti-protozoal and anti-viral (Tasdemir et al. 2004) effects of Rhododendron specieses were also domenstrated by many researches. Although its toxic effect on human and animals, RH is widely used among the population for diseases treatment as inflammation, toothache, skin disorders, edema, gastrointestinal disturbances and colds (Silici et al. 2014b, Tasdemir et al. 2004) Beside its medical therapeutic activity, Rhododendron species and honey obtained from those causes poisoning in humans and animals due to the GTX content of the nectar, pollen, flowers and leaves (Ascioglu and Ozesmi 1995, Koca and Koca 2007). Most of the studies have presented case reports in which toxic symptoms as dizziness, nausea, vomiting, weakness, blurred vision were observed from consuming RH (Ozhan 2004, Gunduz et al. 2008, Koseoglu and Kosenli 2009, Yaylaci et al. 2014, Erenler 2016, Silici et al. 2016).
An Investigation of the Antiproliferative Effect of Rhododendron luteum Extract on Cervical Cancer (HeLa) Cells via Nrf2 Signaling Pathway
Published in Nutrition and Cancer, 2022
Ibrahim Turan, Selim Demir, Serap Ozer Yaman, Deniz Canbolat, Ahmet Mentese, Yuksel Aliyazicioglu
The medicinal use of plants is as old as the history of humanity, and researchers are currently investigating the pharmacological properties of plants used for different purposes in traditional therapies by means of scientific data (9, 34). Rhododendron species are also considered medicinal plants, and identifying their biological activity has become a popular field of research in recent years (11). In studies investigating the biological activities of natural products, plant samples are first milled and pulverized. They are then extracted by means of various solvents, such as ethanol, DMSO, ethyl ether, water, methanol, hexane, and chloroform. Several methods, including maceration, sonication, soxhlet, and microwave extraction, are used to extract active components from natural products (7, 35). In the present study, R. luteum leaves were therefore first dried and powdered, and then extracted by maceration using DMSO as the solvent.