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Herbal Treatment for Irritable Bowel Syndrome
Published in Megh R. Goyal, Preeti Birwal, Durgesh Nandini Chauhan, Herbs, Spices, and Medicinal Plants for Human Gastrointestinal Disorders, 2023
Hasya Nazh Ekin, Didem Deliorman Orhan
Herbal medicines and plant-based products are being used worldwide to treat many diseases or to complement conventional drugs. This section includes discussions on the outcomes of clinical trials in IBS treatment using herbal products.
Secondary Metabolites from Clerodendrum Infortunatum L.: Their Bioactivities and Health Benefits
Published in Hafiz Ansar Rasul Suleria, Megh R. Goyal, Health Benefits of Secondary Phytocompounds from Plant and Marine Sources, 2021
R. L. Helen, K. Jayesh, S. Syama, M. S. Latha
For example, Cannabis sativa is a therapeutic agent for curing rheumatoid arthritis, multiple sclerosis, and AIDS (acquired immunodeficiency syndrome), where the phytoconstituents cannabidiol increases the level of tetrahydro cannabidiol (THC) in the brain. THC alone induces anxiety but the presence of cannabidiol causes attenuation of anxiety. Therefore, the herbs are preferred than isolated compounds for the treatment of multiple sclerosis [86]. Also, plants can be used as preventive medicine because of fewer side effects. This reduces the dependence of synthetic drugs for the treatment of chronic diseases [30]. For example, the consumption of tea is linked with reduced likelihood of diseases and boosts immunity [71]. Medicinal plants are generally considered as safe but there exist evidences that point to the toxicity regarding the use of herbals as medicines [55].
Phytotherapeutic Potential For the Treatment of Alzheimer’s Disease
Published in Atanu Bhattacharjee, Akula Ramakrishna, Magisetty Obulesu, Phytomedicine and Alzheimer’s Disease, 2020
Muhammad Akram, Atanu Bhattacharjee, Naveed Munir, Naheed Akhter, Fozia Anjum, Abida Parveen, Samreen Gul Khan, Muhammad Daniyal, Muhammad Riaz, Fahad Said Khan, Rumaisa Ansari, Umme Laila
AD is a neurodegenerative disease that can severely impair cognitive functions of the brain, ultimately resulting in loss of memory, intellectual ability, disturbance in daily life routine, insomnia, anxiety, and depression due to self-consciousness. Herbal drugs used for the treatment of diseases have pharmacological actions with not well reported side-effects. Several herbs have been used to treat AD. Phytochemicals are present in herbs that prevent the degeneration of proteins, lipids, and neurons. Some herbs contain alkaloid compounds, that are active toward the central nervous system, and which can reduce the oxidative stress of the brain and prevent brain aging. Many research studies have been performed on herbs and it has attracted physicians to use herbs for treatment of diseases because of their beneficial effects. Herbal drugs are successful in providing symptomatic relief while minimizing side effects associated with the administration of synthetic drugs. This chapter concludes that the herbal drugs are not only a more natural way of treatment, but they can be just as effective, if not more so, than the synthetic drugs, but with minimal or no side effects. Medicinal plants, which we discussed above, have antioxidant and anti-inflammatory activities, which play pivotal roles in the treatment of AD. Herbal plants can show significant improvement in cognitive functions in AD patients within six months. The use of appropriate herbal remedies should be encouraged within the specific dosages of the plants approved by the Food and Drug Administration and related regulatory bodies.
Balanitoside as a Natural Adjuvant to Gemcitabine in Lung Cancer Experimental Model
Published in Nutrition and Cancer, 2022
Elsayed I. Salim, Sara S. Aboueisha, Abeer A. Khamis
Plant-derived herbal medicines are widely used for the treatment of a large variety of diseases. In most cases, edible medicinal plants act as adjuvants for cancer therapy and represent a safe choice for immunomodulatory, antimicrobial, antioxidant, anti-inflammatory, and anticancer remedies [28]. In the present study, a quantitative DPPH test on the effects of balanitoside revealed that it exhibits significant antioxidant activity, with an IC50 of 79 mg/mL. Annan and Dickson [29] reported that the IC50 for B. aegyptiaca methanolic extract was 14.6 μg/mL. The presence of flavonoids and phenolic compounds is attributed to the strong antioxidant activity of many plant extracts [30]. The existence of phenolic compounds, saponin, alkaloids, and terpenoids, with significant amounts of total flavonoids and total phenolics, was revealed in the phytochemical analysis of B. aegyptiaca fruit methanolic extract [31].
Comprehensive study on the administrative, economic, regional, and regulatory prospects of complementary and alternative medicine (CAM) in inflammatory bowel disease (IBD)
Published in Expert Review of Clinical Pharmacology, 2021
Taraneh Mousavi, Shekoufeh Nikfar, Mohammad Abdollahi
Nonetheless, over the past two decades, there has been a notable improvement in the number of states regulating herbal medicines, which occurred even at a higher rate than establishing national policies. Regulation for herbal medicines is thoroughly the same as conventional pharmaceuticals in 27 WHO member states, whereas it is somehow different in others. For instance, in Canada, although good manufacturing practice (GMP) is required for the manufacturing of herbal products, it is different from pharmaceuticals regarding the validation of processes and procedures. The partly same regulation for herbal medications (not necessarily for GMP) is also applied in Mexico, Ghana, Niger, Uganda, Bahrain, Iraq, Oman, Serbia, Spain, United Kingdom, Nepal, and Mongolia. Some regions have exclusive regulations for herbal medicines, i.e. Brazil, Pakistan, Yemen, India, Indonesia, and the Lao people’s democratic republic. A case in common is an increment in the use of national or other pharmacopoeia/monographs and GMP guidelines within the indicated period.
The beneficial effects of Ganoderma lucidum on cardiovascular and metabolic disease risk
Published in Pharmaceutical Biology, 2021
Sze Wa Chan, Brian Tomlinson, Paul Chan, Christopher Wai Kei Lam
Cardiovascular disease (CVD) is highly prevalent, with ischaemic heart disease and stroke being the two leading causes of mortality throughout the world (World Health Organization 2021). Metabolic syndrome is characterised by a cluster of conditions including insulin resistance, central obesity, hypertension, dyslipidaemia, and low-grade chronic inflammation (Eckel et al. 2005). Several drug treatments for CVD have been derived from plant sources, such as digoxin and reserpine. Herbal medicines are now becoming more popular, representing a potentially cost-effective class of substances for combating CVD if safe and effective therapies can be identified. The common herbal medicines used in the West include Asian ginseng, astragalus, flaxseed oil, garlic, ginkgo, grape seeds, green tea, hawthorn, milk thistle, and soy (Liperoti et al. 2017). Herbal formulae are widely used in the clinic in China for hypertension, dyslipidaemia, coronary heart disease, and heart failure (Liu and Huang 2016).