China
Africa
Explore chapters and articles related to this topic
Irritable Bowel Syndrome (IBS)
Published in Charles Theisler, Adjuvant Medical Care, 2023
Peppermint oil is a natural antispasmodic that relaxes smooth muscles in the intestines. Studies also show that, in people who have IBS with diarrhea, an enteric coated tablet (Colpermin) that slowly releases peppermint oil in the small intestine eases bloating, urgency, abdominal pain, and pain while passing stoo1.1,4 In one study, IBS patients took Colpermin three to four times daily, 15 to 30 minutes before meals for one month. 79% experienced an alleviation in the severity of abdominal pain, 83% had less bloating, and 79% experienced less flatulence.5 Other studies have confirmed the effectiveness of enteric coated peppermint oil (EPC0).6,7
Monographs of essential oils that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
The essential oil of peppermint, obtained by steam-distillation of the leaves, has many pharmaceutical applications. The European Medicines Agency recently reviewed the pharmacological and clinical literature of peppermint oil and considered two indications as proven and well established: minor spasms of the gastrointestinal tract, flatulence and abdominal pain, especially in patients with irritable bowel syndrome (oral use) and mild tension type headache (cutaneous use) (3). Peppermint oil is also widely employed for flavoring chewing gum, cough drops, sweets, alcoholic drinks, toothpaste, mouth freshener and is also used for perfumes, other cosmetic products and in the tobacco industry. It is also a popular oil in aromatherapy (55).
Aromatic Medicine
Published in Anil K. Sharma, Raj K. Keservani, Surya Prakash Gautam, Herbal Product Development, 2020
Sakshi Bajaj, Himangini Bansal
Peppermint oil has been intensively contemplated for its anti-inflamma-tory, anti-infectious, antimicrobial, and fungicidal impact as well as antiseptics and carminative properties. It is seen that the single constituents of peppermint can calm numerous bacterial, parasitic, and viral contaminations when breathed in or applied as vapor demulcent. On the other side, Ali et al. reported that menthol, the essential constituent of peppermint oil, is responsible for pharmacological activity. It is seen that it can alleviate numerous bacterial, fungal, and viral infections when breathed in or applied in the form of vapor emollient. Sinus and lung blockage are likewise known to be cleared from this oil. Much have been said and examined about the mentha oil by numerous researchers for its different activities yet its utilization in aromatherapy needs more endeavors (Tassou et al., 1995).
Current and emerging pharmacological approaches for treating diarrhea-predominant irritable bowel syndrome
Published in Expert Opinion on Pharmacotherapy, 2020
Akhil Munjal, Bhavtosh Dedania, Brooks D. Cash
Conventional drug therapies for IBS mostly target symptoms of altered stool form (constipation/diarrhea) and bloating and have minimal effects on abdominal pain, which is a major component of IBS symptomatology and significantly affects quality of life. Anti-spasmodics like hyoscyamine, dicyclomine, and peppermint oil have long been used for treating IBS, with the most robust literature supporting peppermint oil. However, side effects from these remedies can limit their utility. Peppermint oil can be associated with bothersome heartburn or dyspepsia. Dicyclomine and hyoscyamine can cause anticholinergic symptoms such as fatigue, dizziness, dry eyes and dry mouth. A small 2-week double-blind study evaluated dicyclomine 40 mg 4 times daily on an ambulatory population and found it to be superior to placebo in controlling overall patient symptoms of pain, abdominal tenderness, and improved bowel habits, albeit with a high incidence of adverse effects [62].
Formulation and evaluation of letrozole-loaded spray dried liposomes with PEs for topical application
Published in Journal of Liposome Research, 2020
Mithun Maniyar, Avik Chakraborty, Chandrakant Kokare
Chemically peppermint oil is an essential oil which increases diffusivity of the drug by changing the SC structure by interacting with the intercellular SC lipids, which leads to the fragmentation of the compact intercellular lipids. Olive oil contains oleic acid as the main fatty acid, which has immense twisted conformation that fluidizes the extracellular lipid area of the SC. Thus, both the natural oils as PEs formed micro-cavities in the lipid bilayers, which create permeable pores that provide a reduced resistance and improved penetration. These outcomes are in good agreement with the earlier established conclusions (Viljoen et al. 2015).