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Monographs of essential oils that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
Angelica archangelica L. is an aromatic, perennial herb that grows up to 2 meter tall. The plant is native to the temperate regions of Asia (Caucasus, Siberia), northern, middle and east Europe, and the Himalayas, and has become widely naturalized in northern temperate regions. The plant is cultivated in Italy, Germany, Finland, Hungary, and several other countries including Korea, India and North America (GRIN Taxonomy for Plants; www.kew.org). Commercial angelica root and fruit oils are mostly obtained from cultivated Angelica archangelica L. ssp. angelica var. sativa (10). Essential oils of the fruits (often incorrectly referred to as ‘seeds’, as the seeds are contained within the fruits) and roots of Angelica archangelica are used for healing purposes, as spice and as fragrance component in perfumery (7) and cosmetics. Angelica root oils are also part of aromatherapy practices (9). The biological activities and medicinal uses of Angelica archangelica L. have been reviewed in references 6 and 8.
Radioprotective efficacy of Ginkgo biloba and Angelica archangelica extract against technetium-99m-sestamibi induced oxidative stress and lens injury in rats
Published in International Journal of Radiation Biology, 2018
Mahmoud H. Khedr, Medhat W. Shafaa, Amany Abdel-Ghaffar, Ahmed Saleh
Angelica archangelica herb belongs to Umbelliferone (a natural product of the coumarin family, occurring in such plants as carrot and coriander). Angelica has many benefits, such as enriching blood, invigorating the circulation of blood and regulating menstrual function (Meng 2007). Angelica polysaccharide is a major element in Angelica. In recent years, the studies of the pharmacology of Angelica polysaccharide have helped in the finding of its apparent effect on the body’s immune and hematopoietic systems, as well as the good curative effect of being anti-tumor, anti-radiation damage and anti-oxidation (Shang et al. 2001; Wang and Shan 2006). Water extraction of A. archangelica roots powder has been reported to be a potent free radical scavenger and an antioxidant against lead toxicity (Elgohary et al. 2009). The main constituents of essential oils of A. archangelica root are pynene, limonene and coumarinosthol that are recently stated to possess antioxidant effects. (Nivinskiene et al. 2003).