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Cardiovascular Drugs during Pregnancy
Published in “Bert” Bertis Britt Little, Drugs and Pregnancy, 2022
Two other drugs that may be given for fetal supraventricular tachycardia: propranolol and procainamide. Verapamil, has been used for this purpose, BUT should be used with extreme caution and usually only after other therapeutic modalities have failed because of potential adverse events. Other efficacious agents include quinidine, disopyramide, flecainide, and amiodarone. The differential treatment decision should be based on the suspected etiology of the tachycardia (Kleinman and Copel, 1991; Copel, 2020).
Heart rate
Published in Andrew R Houghton, Making Sense of the ECG, 2019
Management of tachycardia depends on the underlying rhythm, and the treatment of the different arrhythmias is detailed in the following chapters. The first step, as with managing a bradycardia, is to assess the urgency of the situation – in the peri-arrest situation, use the ABCDE approach and assess the patient for adverse features. The Resuscitation Council (UK) 2015 algorithm on the immediate management of tachycardia (with a pulse) in adults is shown in Figure 5.5. The longer-term management of specific tachycardias is discussed in the chapters which follow.
The electrophysiology laboratory
Published in John Edward Boland, David W. M. Muller, Interventional Cardiology and Cardiac Catheterisation, 2019
This technique is designed to cure certain types of tachycardia. From ECG tracings, it may be possible to identify patients suitable for this technique. There are two broad types of tachycardia that may be suitable for treatment. These are supraventricular tachycardia (SVT) and ventricular tachycardia (VT). These are discussed in Chapters 19 and 20 in more detail.
A review of arrhythmia detection based on electrocardiogram with artificial intelligence
Published in Expert Review of Medical Devices, 2022
Jinlei Liu, Zhiyuan Li, Yanrui Jin, Yunqing Liu, Chengliang Liu, Liqun Zhao, Xiaojun Chen
According to the American Heart Association statistics, cardiovascular diseases (CVDs) have become the primary cause of death in the world [1]. Due to irregular and unhealthy lifestyles, patients with CVDs tend to become younger. The early symptoms of most CVDs are irregular heartbeats, also known as arrhythmia. Arrhythmia is generated by the disordered electrical activity of the heart, and some arrhythmia such as ventricular tachycardia (VT) and ventricular fibrillation (VF) can be life-threatening [2]. In addition, atrial fibrillation (AF), atrial flutter (AFL), premature ventricular contraction (PVC), premature atrial contraction (PAC), paroxysmal supraventricular tachycardia (PSVT), and bradycardia are also common types of arrhythmia [3]. Therefore, rapid detection and accurate diagnosis of cardiac arrhythmia are particularly essential.
Long-term safety of ketamine and esketamine in treatment of depression
Published in Expert Opinion on Drug Safety, 2022
Sina Nikayin, Eva Murphy, John H. Krystal, Samuel T. Wilkinson
Increased heart rate has also been reported in ketamine and esketamine studies, and in the esketamine trials was observed in 1.0–1.6% of the patients [10,49,50]. Clinically significant tachycardia requiring intervention is a rare but important side effect. In the FDA-registered trials of esketamine treatment, tachycardia as a treatment-emergent serious adverse event was reported in one patient out of approximately 1,708. Additionally, heart rate can be affected by psychotomimetic effects of the treatment such as uncomfortable dissociative or dysphoric experiences. Generally, heart rate returns to normal within 60–120 minutes following administration of ketamine or esketamine. Due to the drug’s known but transient effects on both blood pressure and heart rate, providers should be especially cautious upon treating patients with known cardiac pathology.
Unilateral pulmonary edema and acute severe mitral regurgitation associated with operatively repaired aortic coarctation
Published in Baylor University Medical Center Proceedings, 2021
Alireza Nathani, Clinton Jones, Shekhar A. Ghamande, Shirley F. Jones
Despite treatment, hypoxia and tachycardia persisted. Additionally, the patient continued to have 1 L or more of pleural fluid drained from his chest tube daily for over a week. A complete transthoracic echocardiogram revealed severe MR and a structurally abnormal mitral valve (Figure 2). The effective regurgitant orifice area was 0.59 cm2 and the regurgitant volume was 60.1 cc, indicating severe MR. A transesophageal echocardiogram showed a ruptured chordal structure with a flail anterior leaflet, rudimentary and tethered posterior leaflet, and posteriorly directed regurgitation jet. The patient underwent mechanical mitral valve replacement with a 27/29 mm On-X. He tolerated the procedure well. Inspection of the mitral valve revealed that the entire anterior leaflet was pathological, with all of the cords being either elongated or ruptured. Postoperatively, all chest drains were removed. The patient was started on warfarin as a result of his mechanical valve.