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Adhesive and Suture Techniques for Microvascular Anastomoses — a Comparative Experimental Study
Published in Waldemar L. Olszewski, CRC Handbook of Microsurgery, 2019
Harry Heiner, Anneliese Tilgner, Monika Skibbe
Two days after anastomosis histologic investigations showed endothelial defects in all arterial and venous anastomoses, independent of the method of anastomoses. They did not only occur in the suture region, but also in the vascular segments of telescopic anastomoses, obviously as a result of manipulation. The lesions of the internal elastic lamina were also different, according to the techniques applied. Conventional suture anastomoses showed excessive interruptions of the lamina as well as flattening and absence of the indulating structures. In two-suture telescopic anastomoses laminal lesions were limited to both suture lines. The smallest lesions were seen in sutureless telescopic anastomoses joined by means of tissue adhesive. In this case interruptions were obviously due to the needle “pull-through”.
Describe the histology of hypertensive vasculopathy
Published in Nathaniel Knox Cartwright, Petros Carvounis, Short Answer Questions for the MRCOphth Part 1, 2018
Nathaniel Knox Cartwright, Petros Carvounis
Additionally, hypertension causes thickening of the media of muscular arteries and collagen deposition close to the internal elastic lamina. In contrast to the large arteries affected in atherosclerosis, small and medium-sized vessels are especially affected by hypertensive changes.
Cerebrovascular Disease
Published in John W. Scadding, Nicholas A. Losseff, Clinical Neurology, 2011
Temporal arteritis is the most important of the giant cell arteritides. The internal elastic lamina of the extracranial medium-sized arteries becomes fragmented and invaded by inflammatory cells. It virtually always occurs in those over 50 years and is accompanied by an elevated ESR in 90 per cent.
Simultaneous Unilateral Abducens Nerve Palsy and Contralateral Anterior Ischaemic Optic Neuropathy as the Presenting Signs of Giant Cell Arteritis
Published in Neuro-Ophthalmology, 2023
Leonardo E. Ariello, Thais de Souza Andrade, Luiz Guilherme Marchesi Mello, Maria Kiyoko Oyamada, Leonardo Provetti Cunha, Mário L. R. Monteiro
In GCA, the vasculitic process involves transmural inflammation of large and middle-sized arteries.7 Although the inflammatory response starts in the internal elastic lamina, the entire arterial wall can be involved during its progression.8 Visual manifestations are extremely important in the clinical setting of GCA. One of the most serious ocular complications is the involvement of the short posterior ciliary arteries leading to anterior ION, which accounts for approximately 80% of cases with visual loss.9 Posterior ION, choroidal ischaemia, and retinal arterial occlusions are other causes of visual impairment.10 Less commonly but also very importantly, vasculitis may affect the efferent ocular pathway mostly of the distal portion of the oculomotor system, causing diplopia.
The vascular protective effects of trihoney in hypercholesterolemic atherosclerotic rabbits, a comparative study with atorvastatin
Published in Egyptian Journal of Basic and Applied Sciences, 2022
Hamad Abdulsalam Hamad Alfarisi, Muhammad Bin Ibrahim, Zainab Bubakr Hamad Zubi
Masson’s trichrome staining of aortic sections visualized the collagen contents of all stained sections as blue color, while SMCs were stained red color. Atherosclerotic plaques of the trihoney treated group (HCD+H2) had less collagen and more elastin condensed in the upper part of the atherosclerotic plaque. Sections of the control group that were stained by VGS (Figure 3B) showed clear concentric compacted elastic tissue layers (black in color) in tunica media and continuous internal and external elastic laminae. In this normal group, bundles of collagen and SMCs were sandwiched between the elastin layers in tunica media. No elastic tissue fragmentation was found. In contrast, VGS sections from the high cholesterol diet group (Figure 3B) presented a fragmentation of internal and external elastic laminae as well as the disrupted orientation of elastic layers in tunica media, especially at the thickest points of the plaques. Trihoney treated animals (Figures 3) had concentric compact layers of elastic tissues in tunica media, in addition to well retained continuous internal and external elastic laminae. Trihoney treated group that received a higher dose showed condensed elastic tissues in the subendothelial layer, which was not visualized in other atherogenic groups. Atorvastatin received group had compact layers of medial elastic tissues, in addition to evidence of interrupted internal elastic lamina at the thickest points of the atherosclerotic plaque.
Berberine alleviates monosodium glutamate induced postnatal metabolic disorders associated vascular endothelial dysfunction in newborn rats: possible role of matrix metalloproteinase-1
Published in Archives of Physiology and Biochemistry, 2022
Abeer A. Abo Zeid, Ibrahim Rowida Raafat, Abeer G. Ahmed
Ultra structural examination of the aorta of a control rats exhibited that the endothelial cells of the intima were flat and regular continues internal elastic lamina. Smooth muscle cells of the media appeared irregular with branched cells (Figure 5(A,B)). However, that of MSG group revealed that the endothelial cells of the intima became atrophic and degenerated with interrupted internal elastic lamina (Figure 6(A)). The smooth muscle cells of the media showed intra-cytoplasmic fatty deposition (Figure 6(B)). The intima was more atrophied with irregular distribution of the endothelial cells. The sub-endothelial region was apparently thickened with interrupted internal elastic lamina. The smooth muscle cell was seen migrating from the media to the sub-endothelial region (Figure 6(C)). The internal elastic lamina was interrupted and fat droplets could be seen in the cytoplasm of the smooth muscle cell (Figure 6(D)). Infiltrating mononuclear cells could be observed in the sub-endothelial region (Figure 6(E)).