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Complications of axillofemoral, femoral-femoral, and iliac-femoral grafts Diagnosis, Prevention, and Management
Published in Sachinder Singh Hans, Mark F. Conrad, Vascular and Endovascular Complications, 2021
Farah Mohammad, Mitchell Weaver
Axillofemoral bypass's limited patency is the reason it remains an alternate approach to revascularization. 5 year patency has been reported from 35–80%.8 Factors predicting decreased patency include operative indication of arterial occlusive disease, graft material (Dacron vs PTFE) and degree of infra-inguinal arterial occlusive disease. Initial reports of using Dacron non-supported grafts showed higher rates of thrombosis due to compression. However, multiple studies comparing Dacron to externally supported PTFE graft have not shown any significant difference.9 Superficial femoral artery disease has been described in reports to be a predictor of worse outcomes.3
Lower Limb
Published in Bobby Krishnachetty, Abdul Syed, Harriet Scott, Applied Anatomy for the FRCA, 2020
Bobby Krishnachetty, Abdul Syed, Harriet Scott
The main blood supply to the lower limb is by the femoral artery, which is the continuation of the external iliac artery. The femoral artery continues as the popliteal artery in the lower leg (Table 6.1 and Figure 6.3).
Single Best Answer Assessment
Published in John McCafferty, James M Forsyth, Point of Care Ultrasound Made Easy, 2020
John McCafferty, James M Forsyth
An 80-year-old male patient comes to see you (his community physician) in your rural community practice. The patient is complaining of severe pain in his right foot and toes that is present all the time. He is struggling to sleep at night and is now forced to sleep sitting up in a chair. He has also developed a small ulcer on the great toe. These new symptoms started about 3 weeks ago. He also says that when he walks about 20 m he gets severe calf pain that forces him to stop. He has been getting this calf pain for years but it has been gradually worsening. On examination you can only feel a faint femoral pulse, but nothing distally. Using your wireless ultrasound probe you identify a heavily diseased common femoral artery with significantly reduced colour flow. The patient's superficial femoral artery also appears to have a number of areas of stenotic disease. Which of the following statements is correct?
Impact of particle size of multivesicular liposomes on the embolic and therapeutic effects in rabbit VX2 liver tumor
Published in Drug Delivery, 2023
Hailing Tang, Changhui Cao, Guangyuan Zhang, Zhengkao Sun
The embolization procedure was performed under the guide of digital subtraction angiography (Siemens AXIOM Artis FA DSA, Siemens Medical Systems, Erlangen, Germany). Rabbits were anesthetized as described earlier. Vascular access was achieved in the femoral artery through surgical cut down. Celiac angiography was performed to identify the hepatic arterial anatomy and the feeder artery of the tumor using a 3-F catheter (Cook, Bloomington, India). The left hepatic artery, which exclusively supplies blood flow to the tumor, was catheterized selectively. When the catheter was adequately positioned in the left hepatic artery after celiac arteriography was performed, MVLs or 0.9% sodium chloride was injected carefully into the artery according to different groups. Digital spot images were obtained after embolization. The catheter was then removed, and the femoral artery was ligated.
Research progress of portable extracorporeal membrane oxygenation
Published in Expert Review of Medical Devices, 2023
Yuansen Chen, Duo Li, Ziquan Liu, Yanqing Liu, Haojun Fan, Shike Hou
Different cannulation methods may have significant impacts on the patient’s cardiopulmonary support and mobility [40]. The commonly used type of V-A ECMO cannulation is through the femoral artery, studies have confirmed that this type of cannulation is safe for patient mobility. However, there are some potential complications with the femoral artery, including distal limb ischemia [42]. Some recent studies have established circuits through the internal jugular vein and the subclavian or innominate artery, which are more conducive to exercise [43,44]. The internal jugular vein and axillary artery are also used as access points, which can support patients with heart failure to stay active for a longer period of time [45]. For V–VECMO patients, a dual-lumen cannula can be used to establish the ECMO circuit, reducing the number of ECMO cannulation steps and avoiding femoral vein cannulation [46].
Concanavalin A promotes angiogenesis and proliferation in endothelial cells through the Akt/ERK/Cyclin D1 axis
Published in Pharmaceutical Biology, 2022
Jing-Zhou Li, Xiao-Xia Zhou, Wei-Yin Wu, Hai-Feng Qiang, Guo-Sheng Xiao, Yan Wang, Gang Li
Limb ischaemia was conducted in C57/BL6 mice purchased from Vital River Laboratory Animal Technology Company (Beijing, China). Animal care and experimental procedures were performed following instructions of the Institutional Animal Care and the Ethics Committee for animal experiments at Xiamen University (Approval code: XMULAC20170004). A total of 18 male mice were equally assigned to the following 3 groups: Sham group (n = 6), vehicle group (injected with saline solution) (n = 6), and the Con A (10 mg/kg) treatment group (n = 6). In the vehicle and Con A group, the femoral artery of the left hind was excised from its proximal origin as a branch of the external iliac artery to the distal point where it bifurcates into the saphenous popliteal arteries. Then Con A (10 mg/kg) or an equal volume of vehicle was injected into the tissue at 4–5 points around the femoral artery. Tissue perfusion of the hind limbs was assessed with a laser Doppler perfusion imager (Perimed, Stockholm, Sweden). The digital colour-coded images were analyzed to quantify blood flow in the stripped area of the blood vessel.