China
Africa
Explore chapters and articles related to this topic
Tumours of the oral cavity and pharynx
Published in Anju Sahdev, Sarah J. Vinnicombe, Husband & Reznek's Imaging in Oncology, 2020
Kunwar S S Bhatia, Ann D King, Robert Hermans
The floor of the mouth is located beneath the mobile tongue and is enclosed by the lower alveolar ridges. Its inferior boundary includes the sheet-like mylohyoid muscle, separating the floor of the mouth from the submental space below. Its contents are within the sublingual spaces, which include the sublingual and minor salivary glands, the submandibular duct (Wharton duct), and a part of the hyoglossus muscle, as well as the lingual artery, vein, and lingual and hypoglossal nerves. The vessels and nerves are often termed the lingual neurovascular bundle.
Normal Anatomy
Published in Burkhard Madea, Asphyxiation, Suffocation,and Neck Pressure Deaths, 2020
The paired sublingual spaces and submandibular spaces are divided by the mylohyoid muscle and define the floor of the mouth from the mandible to the hyoid bone. They also divide the submandibular and sublingual glands. Anterior dental infections can also extend along the mylohyoid via the SLS space to the SMS space to cause Ludwig's angina and acute airway embarrassment.
Paediatric deep neck space infections
Published in S. Musheer Hussain, Paul White, Kim W Ah-See, Patrick Spielmann, Mary-Louise Montague, ENT Head & Neck Emergencies, 2018
Odynophagia and trismus are typical of PTA and PPA. Sublingual space infection can be rapidly progressive with incipient airway obstruction. Cranial neuropathies may help provide localising information. In some children the infection is so rapidly progressive that they may present with significant sepsis.
Clinical efficacy of sublingual immunotherapy tablets for allergic rhinitis is unlikely to be derived from in vitro allergen-release data
Published in Expert Review of Clinical Immunology, 2019
Giorgio Walter Canonica, Philippe Devillier, Thomas Casale, Pascal Demoly, Catherine Bos, Efstrathios Karagiannis, Giovanni Passalacqua, Ulrich Wahn, Laurent Mascarell
The sublingual holding (swallowing) time affects the time of contact between solubilized allergens and sublingual tissue, because swallowing will remove the majority of unabsorbed allergens from the sublingual space, preventing further uptake. It takes 5 minutes for maximal uptake of allergens by the sublingual tissue, with little uptake within the first minute [32] (Figure 2). In light of this, the sublingual holding time should be at least several minutes. Early swallowing (e.g. at 1 minute) may reduce the uptake of allergens.
Sublingual analgesia: a promising proposal for the treatment of pain
Published in Expert Opinion on Drug Delivery, 2020
Finally, due to the limited volume and surface area of the sublingual space, potency is also an important aspect determining a drug’s utility for sublingual administration. These factors make drugs such as morphine, oxycodone, and hydromorphone, which are strongly hydrophilic and not potent relative to other opioids, have limited utility relative to more potent and lipophilic opioids such as fentanyl, sufentanil, methadone, and buprenorphine for sublingual use.