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The Spread of Chest Tumours to the Abdomen, and some Abdominal Tumours to the Chest - also a consideration of some relevant abdominal conditions in differential diagnosis, particularly of the Liver, Spleen and Pancreas.
Published in Fred W Wright, Radiology of the Chest and Related Conditions, 2022
Splenosis refers to the metastatic spread of splenic tissue following trauma. It was first described by Buchbinder and Lipkoff (1939). Most commonly it is seen in the abdomen, but it may also occur in the chest, particularly if the spleen ruptures into the chest through a traumatic diaphragmatic rupture. Pearson et al. (1978) found recurrent splenic function in 13 out of 22 children who had their spleens removed.
Applied Surgical Anatomy
Published in Tjun Tang, Elizabeth O'Riordan, Stewart Walsh, Cracking the Intercollegiate General Surgery FRCS Viva, 2020
Vishal G Shelat, Andrew Clayton Lee, Julian Wong, Karen Randhawa, CJ Shukla, Choon Sheong Seow, Tjun Tang
What is splenosis? What are the common sites of splenosis?10% of the population has an accessory or extra splenic tissue. This is called splenosis. The common site of splenosis is in the splenic hilum in the vicinity of the tail of the pancreas and splenic ligaments.
Platelet Disorders Douglas Triplett
Published in Genesio Murano, Rodger L. Bick, Basic Concepts of Hemostasis and Thrombosis, 2019
In 5 to 20% of patients with ITP, splenectomy produces little or no lasting benefit. Unfortunately, there is no way of predicting this prior to the operation. The value of splenic sequestration studies is controversial, and currently they are not relied upon. Accessory spleens are mentioned frequently as the cause of failure of splenectomy. Most accessory spleens will be found in the area of the splenic pedicle and can be easily recognized and removed by the surgeon. However, occasionally, distant sites such as lower pelvis, lungs, and liver are encountered, and in these instances the spleen is not easily identified. Rupture of the spleen at surgery may produce splenosis — multiple small areas of splenic tissue in the peritoneum, representing implants of deposited cells. Surgical removal of the accessory spleen may in some instances result in a permanent remission, although not in all cases. Presumably, an exacerbation of the patient’s immune process is responsible for recurrent thrombocytopenia in the majority of cases. In recent years, a number of immunosuppressive drugs have been used in cases of refractory ITP. These have included 6-mercaptopurine, azathioprine, alkylating agents such as Cytoxan® and chlorambucil, and vinka alkaloids such as vincristine.256
Intrapancreatic accessory spleen mimicking pancreatic NET: can unnecessary surgery be avoided?
Published in Acta Clinica Belgica, 2021
Elisabeth Vandekerckhove, Eline Ameloot, Anne Hoorens, Kathia De Man, Frederik Berrevoet, Karen Geboes
Abdominal splenosis is the spontaneous transplantation of splenic tissue to unusual sites. It can occur in any intraperitoneal or extraperitoneal location, nonetheless it is most common in the peritoneum, omentum and mesentery. This situation usually occurs after splenic trauma such as automobile accidents, stab or gunshot wounds and surgery [1]. When there is no history of trauma, another explanation is an accessory spleen, a congenital disorder that develops around the 5th week of gestation with fusion failure of the splenic base in the dorsal mesogastrium during embryological splenic development. An accessory spleen is frequent: autopsy reports revealed an accessory spleen in 10–30% of patients. One study found an abdominal accessory spleen in 16% of 1000 patients who underwent a CT scan. In 80% of these cases, the accessory spleen was located near the splenic hilum, the second most common site was the tail of the pancreas (17%) [2].