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The urinary tract and male reproductive system
Published in C. Simon Herrington, Muir's Textbook of Pathology, 2020
Luis Beltran, Daniel M. Berney
The tumour may spread by lymphatics to the inguinal lymph nodes. However, lymph node enlargement may be reactive in these cases as a result of inflammation associated with the primary tumour.
Penile and urethral cancer
Published in J Kellogg Parsons, E James Wright, The Brady Urology Manual, 2019
Inguinal lymph node management: Risk of inguinal lymph node disease is small (< 10%)Therefore, lymphadenectomy is not indicated.
Urethra and Penis
Published in Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie, Bailey & Love's Short Practice of Surgery, 2018
Professor Sir Norman Williams, Professor P. Ronan O’Connell, Professor Andrew W. McCaskie
Treatment of any associated enlarged inguinal lymph nodes should be delayed until at least 3 weeks after local treatment of the primary lesion. Enlargement caused by infection will usually show signs of subsiding with antibiotic treatment. For palpable nodes, ultrasound-guided fine needle aspiration will confirm the diagnosis and a block dissection of both groins should be undertaken. The management of patients where the nodes are not palpable disease involves the use of sentinel lymph node biopsy (SLNB) followed by inguinal node dissection if the SLNB is positive .
Radiotherapy for postoperative vaginal recurrences of cervical squamous cell carcinoma: analysis of dosing and prognosis
Published in Journal of Obstetrics and Gynaecology, 2023
Ziye Zheng, Ke Hu, Xiaorong Hou, Lihua Yu, Junfang Yan, Fuquan Zhang
All patients who received pelvic EBRT were treated with volumetric modulated arc therapy or helical tomotherapy (n = 91). The Clinical Target Volume (CTV) included all gross tumour, the cervix, paracervical tissue, upper vagina, presacral region and pelvis lymphatic drainage area. The inguinal lymph node drainage area was included when the lower 1/3 of vagina or inguinal lymph node was involved. The retroperitoneal lymphatic drainage area was included when common iliac and/or retroperitoneal lymph node metastasis occurred. The CTV was treated to a median dose 50.4 Gy (range 45.0–50.4 Gy) given as 1.8 Gy-fractions, while the median gross tumour volume (GTV) was 50.4 Gy (range, 45.0–80.2 Gy) boosted by EBRT. The median primary GTV cumulative dose in EQD2 was 67.7 Gy (range, 45 Gy–85.2 Gy) in patients who received only EBRT, while median EQD2 was 70.0 Gy (range, 37.5 Gy–88.9 Gy) in EBRT and BT combined. Twenty-three patients received simultaneously lymph node boosts with doses ranging from 54.0 to 70.0 Gy (median 60.2 Gy), with a median EQD2 of 60.95 Gy.
Lymphatic flow through (LyFT) ALT flap: an original solution to reconstruct soft tissue loss with lymphatic leakage or lower limb lymphedema
Published in Journal of Plastic Surgery and Hand Surgery, 2023
David Guillier, Martino Guiotto, Stephane Cherix, Wassim Raffoul, Pietro G. di Summa
However, when the soft tissue defect is associated with disruption of the lymphatic network, flap-only coverage may not be sufficient avoid lymphorrea, wound breakdown, infections and potential secondary lymphoedema. Anatomically, the lymphatic vessels in the lower leg converge in the medial thigh run parallel to the great saphenous vein and continue to the inguinal lymph nodes above the inguinal ligament. The groin lymph-nodal system is divided into superficial and deep planes within the femoral triangle. The superficial lymph node system drains the lymphatic collectors from the lower limb, superficial gluteal region, lower abdominal wall, perineum and external genitalia. The deep inguinal nodes receive some lymphatic flow from the superficial system (minor part) and then drain to the external iliac nodes [4].
Elke Bräuer-Krisch: dedication, creativity and generosity: May 17, 1961–September 10, 2018
Published in International Journal of Radiation Biology, 2022
Culmination of professional objectives. Severe health crisis. Elke’s professional objectives, based on her achievements, culminated in the preparation of the main components needed for the submission of an ERC Synergy grant (HORIZON 2020) in 2018. However, in February 2016, a black cutaneous lesion was resected at her inner foot edge. Several reoperations followed, including the removal of much enlarged inguinal lymph nodes. Around Christmas 2017, an examination revealed liver and bone metastases. A very stressful immunotherapy 2018 was a very heavy burden to bear. However, Elke was admirably resistant, kept steadily on with her scientific work, as well as with sporting activities such as mountaineering, and traveling with her husband, for instance in Spain, to Fuertoventura, and to Yosemite in California, in May 2018,. Elke, Michael, and their three daughters ready to fly out, had the strong support of their families in France and Germany, their friends and colleagues all over the world, their students, and of their many neighbors at her home in the mountains at Quaix-en-Chartreuse.