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Integrating the Shingo Methodology
Published in Gerhard Plenert, Driving the Enterprise to Sustainable Excellence, 2021
To make a beverage can, the key process steps involve stamping and drawing aluminum discs from rolled stock to form a can shape. The cans are then washed before being labeled, using in-line screen printers. This plant was designed with a quality guarantee concept at every stage of the production process, without the need for final inspection for quality. Speed and quality are the key drivers of process performance, and our QAS (Quality Assurance System), RSVIEW (Rockwell Process Monitoring) system, and RSBizWare (Rockwell Database System) provide real-time production data and process monitoring capability.
Prostate histological investigation in rats exposed to bisphenol a and phytochemicals during the perinatal period and subjected to hormonal stimulus in adulthood
Published in International Journal of Environmental Health Research, 2022
Thainá Cavalleri Sousa, Camila Bonillo de Oliveira, Maria Luiza Silva Ricardo, Ariana Musa de Aquino, Wellerson Rodrigo Scarano, Allice Santos Cruz Veras, Maria Eduarda Almeida Tavares, Giovana Rampazzo Teixeira, Anthony César deSousa Castillho, Francis Lopes Pacagnelli, Joyce Zalotti Brandt, Leonardo de Oliveira Mendes
Bisphenol A (BPA), an endocrine disruptor, is widely used in epoxy resins and polycarbonate plastics and is present in everyday consumer products such as baby bottles and beverage can linings, and interferes with the endocrine system. The widespread use of BPA has been a cause of concern due to the increasing rate of human exposure to this chemical and because it can trigger toxic effects even at low concentrations (Zhou et al. 2019). The United States Environmental Protection Agency indicated that less than 1 µg/kg body weight/day of BPA is safe for humans. However, recent studies have shown that administering 0.2 µg/kg body weight/day of BPA can cause serious consequences, such as lower sperm production and reduced fertility in male animals (Hafezi and Abdel-Rahman 2019).