Explore chapters and articles related to this topic
Swelling Studies on Hydrogel Blend Used in Biomedical Applications
Published in Anandhan Srinivasan, Selvakumar Murugesan, Arunjunai Raj Mahendran, Progress in Polymer Research for Biomedical, Energy and Specialty Applications, 2023
Shreyas Devanathan, Sheila Devasahayam, Sri Bandyopadhyay
PVA is a linear synthetic polymer produced via partial or full hydrolysis of polyvinyl acetate to remove the acetate groups. PVA is used in controlled drug delivery systems, dialysis membrane, wound dressing, artificial cartilage and tissue engineering scaffold (Zhou et al., 2010), as well as in artificial pancreas, synthetic vitreous body, artificial skin and cardiovascular devices (Abd El-Mohdy & Ghanem, 2009). It is used as a suture material for tight tying, artificial tendons, artificial ligaments and reinforcing fibres for biocomposites in the synthesis of membranes for use in artificial pancreas material (Gough, Scotchford & Downes, 2002). The biodegradability and water solubility of PVA ensure easy degradation and elimination after its use (Park, Park & Ruckenstein, 2001).
Ligno project: Development of composite waste material from wood and MDF applied to the design
Published in Paulo Jorge da Silva Bartolo, Fernando Moreira da Silva, Shaden Jaradat, Helena Bartolo, Industry 4.0 – Shaping The Future of The Digital World, 2020
G.R. Corrêa, M.L.A.C. de Castro, J.C. Braga, F. Moreira da Silva
Considering the above, from the Ligno Project, a composite material was developed as an alternative for the reuse of solid wood residues and MDF. The Ligno also promoted the development of the design of two products for experimentation of the composite material. The manufacturing process of the products occurs by thermoforming in a closed matrix and the morphology of the products is exactly the same as the counterform of the matrix used. In this way, it is possible to obtain complex shapes for the application in products of high added value, without the need for further machining or treatment. The adhesive used is polyvinyl acetate (PVA), because it is economically more accessible, environmentally suitable and not widely exploited in this type of application.
Pharmaceutical Applications of Water-Soluble Polymers in Nanomedicine and Drug Delivery
Published in Shaker A. Mousa, Raj Bawa, Gerald F. Audette, The Road from Nanomedicine to Precision Medicine, 2020
Schuyler A Pruyn, Mehdi Rajabi, Mary Adeyeye, Shaker A. Mousa
Poly(vinyl alcohol) (PVA) is soluble in highly polar and hydrophilic solvents, such as dimethyl sulfoxide, ethylene glycerol and water. It is synthesized by the polymerization of vinyl acetate to polyvinyl acetate, which is then hydrolyzed to get PVA. PVA hydrogels, which are ideal biomaterials because of their non-toxic, non-carcinogenic, and bio-adhesive nature, have been used for various biomedical and pharmaceutical applications. PVA hydrogels are readily accepted into the body and have been used for contact lenses, the lining of artificial hearts, and drug delivery systems. In recent years, much research has been done on PVA films or gels obtained by the addition of salts to aqueous PVA solutions [90].
Novel high-strength thromboresistant poly(vinyl alcohol)-based hydrogel for vascular access applications
Published in Journal of Biomaterials Science, Polymer Edition, 2020
Matthew M. Mannarino, Michael Bassett, Daniel T. Donahue, James F. Biggins
Polyvinyl alcohol (PVA) is a linear synthetic polymer produced via the hydrolysis of polyvinyl acetate to remove the acetate groups. PVA is a water-soluble polymer that can be converted into a water-swelling hydrogel by providing chemical or physical cross-links. The properties of the PVA hydrogel are dependent on a number of factors such as degree of hydrolysis, molecular weight, cross-link density, and type of cross-link(s) [24, 25]. Numerous cross-linking methods have been investigated for PVA including: freeze-thaw induced crystallization [26–29], heat-treatment [30, 31], acid-catalysed dehydration [32], irradiation [33], and the use of aldehyde [34] or alkoxysilane cross-linkers [35]. Many of the chemical cross-linking methods utilize toxic cross-linking agents that could potentially compromise the biocompatibility of the PVA hydrogel and the physical cross-linking methods do not produce hydrogels with substantial strength to be used as mechanically robust constructs for durable vascular access devices and implants such as power-injectable catheters or bypass grafts.
Analysis of the physicochemical properties of antimicrobial compositions with zinc oxide nanoparticles
Published in Science and Technology of Advanced Materials, 2019
Jolanta Pulit-Prociak, Jarosław Chwastowski, Laura Bittencourt Rodrigues, Marcin Banach
PVA is a synthetic polymer obtained through the hydrolysis of polyvinyl acetate. It is biodegradable, water-soluble, hydrophilic, non-toxic, and biocompatible. PVA also presents good film forming and mechanical properties [49,50]. Films of PVA can be obtained through a solution casting technique. Due to its biodegradability, PVA is commonly applied in blends with biopolymers such as cellulose derivatives and gelatine for obtaining flexible films [51–53].
Development of biomimetic electrospun polymeric biomaterials for bone tissue engineering. A review
Published in Journal of Biomaterials Science, Polymer Edition, 2019
Sugandha Chahal, Anuj Kumar, Fathima Shahitha Jahir Hussian
PVA is a synthetic polymer, used since the early 1930s, in a wide range of industrial, commercial, medical and food applications including resins, lacquers, surgical threads and food-contact applications [183]. PVA is commercially produced by partial or full hydrolysis of polyvinyl acetate by removing the acetate group (see Figure 17). The chemical, physical and mechanical properties of PVA depend on the amount of hydrolysis [184].