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Microwave-Assisted Extraction of Carvone From Carum Carvi
Published in Bharat A. Bhanvase, Rajendra P. Ugwekar, Raju B. Mankar, Novel Water Treatment and Separation Methods, 2017
O. D. Borole, S. R. Shirsath, S. G. Gaikwad
Carvone exists in two enantiomeric forms, S-(+) carvone and R-(–) carvone; both are naturally occurring compounds. Caraway seed oil contains S-(+) carvone as major component, whereas R-(-) carvone is found in spear- mint oil.5 Carvone is used to inhibit sprouting of potatoes and is used as fungistatic as well as bacteriostatic.6 It is also used as an insecticide, mosquito repellent, and perfume ingredient, for flavoring of food stuff, and as a starting material for the synthesis of different compounds of high medical relevancy.7 The main source of carvone recovery is caraway seed, and the recovery has been carried out by a number of researchers using conventional extraction techniques such as steam distillation, hydrodistillation, Soxhlet extraction, etc.8 Non-conventional techniques that have been used to extract caraway essential oil are supercritical fluid extraction,9−11 microwave-assisted extraction (MAE),12 and ultrasound-assisted extraction (UAE).13
Greener Synthesis of Natural Products
Published in Ahindra Nag, Greener Synthesis of Organic Compounds, Drugs and Natural Products, 2022
Renata Kołodziejska, Renata Studzińska, Hanna Pawluk, Alina Woźniak
The same cells, R. erythropolis DCL14, selectively in the biphasic system n-dodecane:water oxidize (-)-trans-carveol to (-)-carvone, giving a greater than 98% diastereomeric excess when the (-)-carveol conversion was 59% (Figure 14.39). R-(-)-Carvone is used for air-freshening products and, like many essential oils, oils containing carvones are used in aromatherapy and alternative medicine. S-(+)-Carvone has shown a suppressant effect against high-fat diet-induced weight gain in mice.137,138
Investigation and optimisation of the extraction of carvone and limonene from the Iranian Mentha spicata through the ultrasound-assisted extraction method
Published in Indian Chemical Engineer, 2022
Sepideh Mansoori, Hossein Bahmanyar, Elnaz Jafari Ozumchelouei, Iman Najafipour
The main active constituent of spearmint extract is carvone, which gives spearmint its specific scent. Carvone is a monoterpene hydrocarbon with two enantiomers, namely (−)–carvone and (+)–carvone. It is well established that both optical isomers of carvone are active against a wide spectrum of human pathogenic fungi and bacteria [4] and exhibit antioxidant, antimicrobial, and antifungal effects [5]. Limonene is the second predominant component of the spearmint extract. Similar to carvone, limonene is a cyclic monoterpene with two isomeric forms: (+)–limonene and (−)–limonene. Limonene is a useful natural compound with a wide range of applications in medicine, such as managing inflammation, assisting digestion, and to alleviate depression [6]. Besides, the antitumor properties of Limonene have made it a valuable substance for the prevention or treatment of cancer [7]. Extraction is the first step in the isolation of active ingredients from various plants. Limonene is highly soluble in ethanol and carbon tetrachloride [8]. The combination of water and organic solvents provide higher extraction efficiency in comparison with the pure solvents [9]. For the extraction of phenolic compounds, the mixture of 80% v/v ethanol–water resulted in the highest extraction yield [10].