Vaccine efficacy

Vaccine efficacy

Measures of Association and Public Health Impact

Published in Frank R. Spellman, Fundamentals of Wastewater-Based Epidemiology, 2021

In calculating the risk of disease among vaccinated and unvaccinated persons and determining the percentage reduction in the risk of disease among vaccinated persons relative to unvaccinated persons the vaccine efficacy/effectiveness (VE) is measured. The greater the percentage reduction of illness in the vaccinated group, the greater the vaccine efficacy/effectiveness. The basic formula is written as:Riskamongunvaccinatedgroup–riskamongvaccinatedgroupRiskamongunvaccinatedgroupOR:1−riskratio

On Fixed-Width Confidence Limits for the Risk Ratio with Sequential Sampling

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Journal Information

Published in American Journal of Mathematical and Management Sciences, 2020

Hokwon Cho, Zhou Wang

One of the most important measures in epidemiology research is related to vaccine efficacy or effectiveness of the diseases under study. The vaccine efficacy (VE) is defined as a proportionate reduction in disease attack rate between the unvaccinated and vaccinated study cohorts and calculated by means of the following equation; where πU denotes the flu attack rate of unvaccinated group (ARU), πVdenotes the flu attack rate of vaccinated group (ARV), and is the relative risk of occurring in the vaccinated compared to the unvaccinated (see also, Weinberg & Szilagyi, 2010). The estimated vaccine efficacy is then

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Measures of Association and Public Health Impact

On Fixed-Width Confidence Limits for the Risk Ratio with Sequential Sampling