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XEN Gel Implant: a new surgical approach in glaucoma
Published in Expert Review of Medical Devices, 2018
Ankita Chaudhary, Lauriane Salinas, Jacopo Guidotti, André Mermoud, Kaweh Mansouri
Trabeculectomy is the most commonly performed incisional surgical procedure to lower IOP. It consists of excision of a small portion of the trabecular meshwork and adjacent corneoscleral tissue to provide a pathway for drainage of aqueous humor from within the eye to under the conjunctiva where it is absorbed. Despite its widespread use, trabeculectomy has its limitations. Apart from the short-term problems like near 50% rate of transient perioperative complications [15], the long-term rate of failure has been reported to be as high as 50% at 5 years, even with adjunctive 5-FU (Fluorouracil) or mitomycin C (MMC), as reported in ‘the tube versus trabeculectomy study’ [16].