Terpenoids Against Infectious Diseases
Published in Dijendra Nath Roy, Terpenoids Against Human Diseases, 2019
Sanhita Ghosh, Kamalika Roy, Chiranjib Pal
In 2014, Bukvicki et al. studied the effect of Satureja horvatii oil against certain Gram-positive and -negative bacteria in vitro. According to his work, Satureja horvatii oil showed significant effects against Staphylococcus aureus, Salmonella typhimurium, Listeria monocytogenes and Escherichia coli (Bukvicki et al. 2014). The major constituents of this oil were p-cymene (33.14%) and thymol (26.11%) (Table 8.1). In a singular experiment, a minimal concentration of p-cymene completely inhibited the growth of Escherichia coli, Vibrio parahaemolyticus, Listeria monocytogenes and Salmonella enterica. Similarly, at a concentration of 6 mg/mL, Staphylococcus aureus, Streptococcus mutans and, at a concentration of 3 mg/mL, Streptococcus sanguinis, were found to be inhibited. Moreover, p-cymene was found to exert synergistic effects along with 4-terpineol, linalool and α-terpineol (Table 8.1), against Salmonella enterica, Staphylococcus aureus and Streptococcus sanguinis (Marchese et al. 2017).