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Low-coherence interferometry
Published in Pablo Artal, Handbook of Visual Optics, 2017
Modern ophthalmology has tremendously benefitted from advanced imaging methods and high-precision metrology techniques. Optical biometry is nowadays the standard technology for measuring intraocular distances as, for example, the axial eye length, which is needed for an accurate determination of the lens power of artificial intraocular lenses used to replace cataract lenses. For this application, optical biometry has largely replaced the previously used ultrasound ranging technique due to its higher precision, resolution, and contact-free application. Retinal diagnostics has been dramatically improved by the introduction of imaging techniques such as scanning laser ophthalmoscopy (SLO), fluorescein angiography, scanning laser polarimetry, and adaptive optics (AO) flood illumination cameras and SLOs. While these techniques are able to image retinal structures with high transverse resolution, their depth resolution is limited by the numerical aperture (NA) of the eye to about 300 μm (or about 50 μm if AO technology is used). This prevents the use of these technologies for imaging and quantifying individual retinal layers.
Studies on Registration and Fusion of Retinal Images
Published in Rick S. Blum, Zheng Liu, Multi-Sensor Image Fusion and Its Applications, 2018
France Laliberté, Langis Gagnon
The scanning laser ophthalmoscope (SLO) is used to take fluorescein and indocyanine-green angiograms, measure scotomas, topography and tomography of structures, and so forth. It is a very low-light imaging device compared to the fundus camera because it uses a focused laser beam as illumination source, allowing the remaining pupil area to collect the light.1 It provides a better resolution than the fundus camera. It is useful, in its infrared mode, to detect the choroidal neovessels.
Recent advances in imaging technologies for assessment of retinal diseases
Published in Expert Review of Medical Devices, 2020
Taha Soomro, Neil Shah, Magdalena Niestrata-Ortiz, Timothy Yap, Eduardo M. Normando, M. Francesca Cordeiro
AO-OCT, however, is unable to detect fluorescent signals [49]. Combined with scanning laser ophthalmoscopy (SLO), AO-SLO can detect fluorescent signals, allowing retinal microvasculature and associated blood flow imaging. This has higher resolution than more conventional FFA resulting in more detailed information about the retinal capillary network and benefits from being non-invasive. Limitations at present include the small field of view obtained, meaning peripheral pathology is difficult to image [49]. Newer advancements include combining AO-SLO with AO-OCT allowing high resolution and tracking capabilities [50].