Pulp necrosis

Pulp necrosis

Dentin-Pulp Complex Regeneration

Published in Vincenzo Guarino, Marco Antonio Alvarez-Pérez, Current Advances in Oral and Craniofacial Tissue Engineering, 2020

Amaury Pozos-Guillén, Héctor Flores

Dental caries may end up in pulpal necrosis and potential tooth loss if not treated. Three basic reactions protect the pulp against caries: (i) a decrease in dentin permeability, (ii) tertiary dentin formation, and (iii) inflammatory and immune reactions. These responses occur concomitantly, and their robustness is highly dependent on the aggressive nature of the advancing lesion (Smith 2002). There are different factors about the dental pulp response that distinguish it from other tissues in the body. Clinically and histologically, the pulpal response to aggressions has been well studied.

Advanced materials and technologies for oral diseases

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Journal Information

Published in Science and Technology of Advanced Materials, 2023

Hao Cui, Yan You, Guo-Wang Cheng, Zhou Lan, Ke-Long Zou, Qiu-Ying Mai, Yan-Hua Han, Hao Chen, Yu-Yue Zhao, Guang-Tao Yu

Permanent teeth with pulp necrosis inevitably lose the natural biological defenses inherent in the pulp and are prone to fracture over time, which seriously affects the survival rate of the teeth [93]. Pulp regeneration is one of the most desirable treatments for pulp infections, especially for young permanent teeth. The process of pulp regeneration is to promote the continuous development of teeth by promoting angiogenesis under the premise of ensuring antibacterial activity.

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Dentin-Pulp Complex Regeneration

Advanced materials and technologies for oral diseases