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Essential Inquiries: Dose, Benefit, and Risk in Medical Imaging
Published in Lawrence T. Dauer, Bae P. Chu, Pat B. Zanzonico, Dose, Benefit, and Risk in Medical Imaging, 2018
Pat B. Zanzonico, Bae P. Chu, Lawrence T. Dauer
In addition to PET-CT scanners, SPECT-CT scanners are now commercially available. The design of SPECT-CT scanners is similar to that of PET-CT scanners in that the SPECT and CT gantries are separate and the SPECT and CT scans are acquired sequentially, not simultaneously. In such devices, the separation of the SPECT and CT scanners is more apparent because the rotational and other motions of the SPECT detectors effectively preclude encasing them in a single housing with the CT scanner. PET-MRI scanners have recently been introduced; these allow simultaneous, rather than sequential, acquisition of the PET and MRI studies.
Quantitative analyses and case studies of hybrid PET-MRI imaging
Published in Yi-Hwa Liu, Albert J. Sinusas, Hybrid Imaging in Cardiovascular Medicine, 2017
Leon J. Menezes, Eleanor C. Wicks, Brian F. Hutton
The main motivation for the development of PET/MRI scanners was to take advantage of the superior soft tissue contrast of MRI and the reduced ionizing radiation exposure in comparison to PET/computed tomography (CT). But there are other advantages specific to cardiac imaging that might be exploited, e.g., the dynamic imaging of the ventricle for improved correction for motion and respiration. However, there are difficulties for quantitative analysis when the generation of attenuation correction (AC) maps of the patient is directly from MRI data.
Introduction
Published in A Stewart Whitley, Jan Dodgeon, Angela Meadows, Jane Cullingworth, Ken Holmes, Marcus Jackson, Graham Hoadley, Randeep Kumar Kulshrestha, Clark’s Procedures in Diagnostic Imaging: A System-Based Approach, 2020
A Stewart Whitley, Jan Dodgeon, Angela Meadows, Jane Cullingworth, Ken Holmes, Marcus Jackson, Graham Hoadley, Randeep Kumar Kulshrestha
PET–MRI also continues to progress; however, at the time of writing, PET–MRI systems remain at a significantly higher cost, due to their complex technology. PET–MRI has the added value of not using ionising radiation and providing greater soft tissue detail. Equally the functional imaging qualities of MRI are why this is considered of benefit in neurology imaging and research. Nonetheless, the mainstay of PET is currently in oncology, for which PET–CT systems fulfil the required demand.
Overview of the application of inorganic nanomaterials in breast cancer diagnosis
Published in Inorganic and Nano-Metal Chemistry, 2022
Asghar Ashrafi Hafez, Ahmad Salimi, Zhaleh Jamali, Mohammad Shabani, Hiva Sheikhghaderi
In other combinations, since both PET and MRI have some significant advantages in comparison with PET/CT, thus PET can couple by MRI for improving PET/CT.[93] By this way the applications of this method has certainly made several progress in the diagnosis of the disease.[94] Surprisingly, one of the remarkable differences in PET/MRI relative to PET/CT scan is the elimination of ionizing radiation during imaging, nevertheless coupling of MRI and PET have some challenges such as the sensitivity of PET detector against the applied external magnetic field.[29] Consequently, PET detectors must put within the MRI hole that there is limited space available for PET detectors (Figure 3). Unlike the PET/CT scan, PET/MRI images have a high contrast for soft-tissue, and also it is an additional imaging method to collect the excess data from the disease. In summary, despite the numerous breakthroughs existence in the combination of molecular imaging techniques, there are still some concerns about efficiency along with the accuracy diagnosis regarding targeting and sensitivity terms of all mentioned classical imaging methods.[29,93]
Non-invasive imaging techniques to assess myocardial perfusion
Published in Expert Review of Medical Devices, 2020
Olivier Villemain, Jérôme Baranger, Zakaria Jalal, Christopher Lam, Jérémie Calais, Mathieu Pernot, Barbara Cifra, Mark K. Friedberg, Luc Mertens
Ultimately, it seems intuitive to say that the next generation of imaging for myocardial perfusion analysis will be hybrid (or fusion) techniques combining several techniques and combining their strengths. The CT-SPECT combination (Figure 5) is one possible example, as is the Ultrasound-PET combination. Since 2010, hybrid PET/MRI using sequential and integrated scanner platforms has been available, with hybrid cardiac PET/MR imaging protocols increasingly incorporated into clinical workflows. Given the range of complementary information provided by each method, the use of hybrid PET/MRI may be justified and beneficial in particular clinical settings for the evaluation of different disease entities. Indeed, as summarized in this Review paper, each technique has its inherent limitations in the underlying physics. But being able to combine the advantages of each would allow research and medical teams to go further in the analysis of myocardial perfusion. Through the development of other technologies, such as machine learning, automatic image analysis, or potential robotization (for the automatic performance of echocardiography), the association and combination of imaging techniques will become more accessible and reliable.
Liminal innovation practices: questioning three common assumptions in responsible innovation
Published in Journal of Responsible Innovation, 2018
In contrast with the first assumption, research projects and developments in medical technology are not typically focused on the development of radically novel technology. Rather, the simple addition of another variable – whether spatial, temporal, contextual, or technological – can lead to the emergence of a technological innovation. cEEG, for instance, consists of a new application of an existing technology. Instead of having the EEG record one moment in time or at intervals, it now records continuously for 72 hours. Other examples of ‘new application, old technology’ can occur by combining two existing technologies. For example, combining a positron emission tomography (PET) scanner with a computed tomography (CT) scanner led to the creation of the PET-CT. This development, in turn, helped spark the combination of PET (functional imaging) with magnetic resonance imaging (MRI, soft tissue morphological imaging), from which the PET-MRI emerged.