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Designing for Head and Neck Anatomy
Published in Karen L. LaBat, Karen S. Ryan, Human Body, 2019
The venous blood from the head flows back toward the heart through the four major veins of the neck, the R and L internal jugular veins and R and L external jugular veins (Figure 3.13). The veins lie adjacent to the carotid artery at the side and near the front of the neck.
The possible role of the seaweed Sargassum vulgare as a promising functional food ingredient minimizing aspartame-associated toxicity in rats
Published in International Journal of Environmental Health Research, 2022
Rasha Y. M. Ibrahim, Huda B. I. Hammad, Alaa A. Gaafar, Abdullah A. Saber
At the end of the experiment, the rats were mildly anesthetized and blood was collected from the internal jugular vein in dry clean covered tubes. Blood samples were centrifuged at 4000x g for 10 min. The clear sera were separated and kept in a deep freezer at – 20°C until further biochemical analyses. Next, all the rats were sacrificed under deep anesthesia. Spleen organs were immediately and carefully excised from each rat. A part of the spleen tissue in each rat was used to prepare 10% homogenate. Briefly, spleen tissues were washed with an ice-cold saline NaCl solution (0.9%, w/v), and homogenized using a glass homogenizer (Glas-Col Homogenizer, Terre Haute, USA). Each organ was separately homogenized in a chilled saline to yield 10% (w/v) spleen tissue homogenate. The homogenates were centrifuged using a cooling centrifuge (Universal 32 R, Germany) at 10000x g for 20 min at 4°C. The resultant supernatant was divided into several aliquots and stored at – 80°C prior to the biochemical assays. Other parts of the spleen tissues were preserved in 10% buffered formalin for histopathological examination.
CardioMEMSTM System in the Daily Management of Heart Failure: Review of Current Data and Technique of Implantation
Published in Expert Review of Medical Devices, 2020
Muhammad Asif Mangi, Zeid Nesheiwat, Rehan Kahloon, George V. Moukarbel
A 77-year-old man with a history of systolic heart failure due to nonischemic cardiomyopathy. He was in NYHA Class III symptoms with multiple readmissions for acute systolic heart failure exacerbation. He was referred for placement of CardioMEMSTM PA sensor. Using ultrasound guidance and micropuncture technique, the internal jugular vein was accessed. A Swan-Ganz catheter was advanced and used to perform right heart catheterization and to perform selective left pulmonary arteriography. The CardioMEMSTM PA sensor device was advanced over the Command wire 0.018 into the left pulmonary artery. At that point, there was inability to advance the delivery catheter of the CardioMEMSTM device over the wire. The wire was then pulled back, but it was locked in the delivery catheter and would not advance nor pullback inside the delivery catheter. We then decided to retrieve the assembly including the wire, delivery catheter, and PA sensor. The wire was stuck and could not separate from the catheter itself. This particular device was discarded and was returned to the manufacturer for examination. A new CardioMEMSTM device and delivery catheter were then advanced over the wire to the target site and the CardioMEMSTM device was deployed at that location with no issues [Figure 3].
Mechanical circulatory support for the right ventricle in combination with a left ventricular assist device
Published in Expert Review of Medical Devices, 2019
Shogo Shimada, Kan Nawata, Osamu Kinoshita, Minoru Ono
The TandemHeart RVAD uses an extracorporeal centrifugal-flow pump and two 21-F venous cannulas to deliver blood from the RA to the PA. Most TandemHeart RVAD cannulas are deployed via both femoral veins. For bilateral femoral cannulation, the outflow cannula is placed in the PA via the right femoral vein, and the inflow cannula is placed in the RA via the left femoral vein. Alternatively, the outflow cannula can be placed in the PA via the right internal jugular vein [46]. Recently the PROTEK Duo dual-lumen coaxial cannula was developed [6,47,48]. This new cannula, which is positioned via the right internal jugular vein, contains two lumens within one 29-F or 31-F cannula. One lumen serves as an inflow cannula and encompasses a series of inflow vents positioned across the superior vena cava into the RA. The second lumen has a multi-fenestrated distal tip to deliver blood into the PA. The inflow cannula drains blood from the RA into an extracorporeal centrifugal-flow pump, which delivers blood back to the PA. Because of its internal jugular cannulation site, this configuration allows ambulation during support. In addition, this system can provide both RV support and improved oxygenation by splicing an oxygenator into the circuit. The PROTEK Duo cannula and TandemHeart pump are approved for clinical use for a period of up to 30 days by the European Medicines Agency and up to 6 days by the U.S. Food and Drug Administration. Feasibility of early rehabilitation and oxygenation support is a potential advantage of this system over the Impella RP.