Hepatoblastoma – Knowledge and References

Hepatoblastoma

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Paediatrics

Published in David A Lisle, Imaging for Students, 2012

Hepatoblastoma is the most common hepatic tumour in children. Hepatoblastoma has an increased incidence in Beckwith–Weidemann syndrome, hemihypertrophy and biliary atresia; it is not associated with cirrhosis. Most hepatoblastomas occur under the age of three.

Pistacia lentiscus L. fruits showed promising antimutagenic and antigenotoxic activity using both in-vitro and in-vivo test systems

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Journal Information

Published in Journal of Toxicology and Environmental Health, Part A, 2022

Ghania Bouguellid, Nadjet Debbache-Benaida, Dina Atmani-Kilani, Chiara Russo, Margherita Lavorgna, Concetta Piscitelli, Karima Ayouni, Meriem Berboucha-Rahmani, Marina Isidori, Djebbar Atmani

Another aim was to examine cytotoxic potency by testing extracts on human cancer cell lines human hepatoblastoma (HepG2) and breast adenocarcinoma (MCF-7) (two among the most widespread cancers) utilizing MTT assay. Then, to understand if extracts were able to exert selective toxicity towards cancer cells, the antiproliferative activity observed on cancer cells was compared with that of human normal-like fibroblast cell line (TelCOFS02MA).

Recent advances in PET probes for hepatocellular carcinoma characterization

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Journal Information

Published in Expert Review of Medical Devices, 2019

Luca Filippi, Orazio Schillaci, Oreste Bagni

It is worth mentioning that PET with 11C-acetate proved useful for the imaging of hepatoblastoma, the most common primary liver malignancy in children: in a 6-year-old girl previously treated for hepatoblastoma, PET with 11C-acetate was able to detect an occult bony localization [44].