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Computer Aided Diagnosis in Pre-Clinical Dementia: From Single-Modal Metrics to Multi-Modal Fused Methodologies
Published in Ayman El-Baz, Jasjit S. Suri, Big Data in Multimodal Medical Imaging, 2019
Yi Lao, Sinchai Tsao, Natasha Lepore
Comparing to controls, CCs in the MCI-h group presented similar but more extensive alterations than those from the MCI-l group, suggesting an ‘interactive’ impact of the vascular and neurodegenerative factors on brain morphometry. These are generally in line with anatomical findings showing associations between vascular brain injuries or risk factors and aggregated brain atrophy, especially in the parietal and temporal lobe [10,99]. In terms of the comparison within MCI subgroups, significant differences resided in the dorsal anterior CC, implying an ‘additive’ effect of vascular pathology on the brain frontal network that is differentiable from the non-vascular neurodegeneration influences. The frontal lobe hypo-perfusion detected by ASL-MRI has been reported to be associated with worse executive and memory function [100]. Vascular risk factors measured by FCRP and high-density lipoprotein cholesterol are found to link with thinner frontotemporal cortex [99]. In the presented study, the distinctive impact of the cardiovascular factor in the genu of CC is consistent with the anatomic relationship between cognitive profile and the frontal lobe [99] and provides further neuroanatomic evidence supporting the neuropsychological findings of the selective executive dysfunction of vascular pathology [25,26,75].
3D morpho-topological analysis of asymmetric neuronal morphogenesis in developing zebrafish
Published in João Manuel, R. S. Tavares, R. M. Natal Jorge, Computational Modelling of Objects Represented in Images, 2018
S. Härtel, J. Jara, C.G. Lemus, M.L. Concha
Recently, 3D invariant moments have been reported to provide good discriminatory power to identify handedness- and sex-correlated shapes of the cortical sulci in brain morphometry (Mangin et al. 2004). The general low acceptance of invariant moments in biological and medical science might be caused by the slightly abstract formalism (see [2,3]). Nevertheless, the invariants up to the power of 2 have a direct physical relevance: they define the principal rotational axis of a solid body of homogeneous or heterogeneous mass distribution (ρ (x,y,z) = 1 or ρ (x,y,z) = f(x,y,z)).
Computer Vision in Surgical Operating Theatre and Medical Imaging
Published in Lavanya Sharma, Mukesh Carpenter, Computer Vision and Internet of Things, 2022
Mukesh Carpenter, Dharmendra Carpenter, Vinod Kumar Jangid, Lavanya Sharma
CV technologies are used as an adjunct to MRI brain interpretation as the AI-Rad Companion Brain MR for Morphometry Analysis can automatically detect roughly 30 brain segments on MRI images, calculate their volumes, and compare the outcomes to data in a normative reference database for brain morphometry from the Alzheimer’s Disease Neuroimaging Initiative [8].
Tumor Segmentation by a Self-Organizing-Map based Active Contour Model (SOMACM) from the Brain MRIs
Published in IETE Journal of Research, 2022
G. Sandhya, Giri Babu Kande, T. Satya Savithri
Skull stripping [40] is an important phenomenon in brain image analysis. Numerous applications, like cortical surface reconstruction, pre-surgical planning, and brain morphometry, depend on accurate segmentation of brain region from non-brain tissues such as skin, skull, eyeballs, etc.