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Relevance of Bio-Inks for 3D Bioprinting
Published in Atul Babbar, Ankit Sharma, Vivek Jain, Dheeraj Gupta, Additive Manufacturing Processes in Biomedical Engineering, 2023
Bhargav Prajwal Pathri, Mohd. Shahnawaz Khan, Atul Babbar
Three-dimensional (3D) bioprinting is the 3D printing of bio-inks in a specific shape of an organ so that the cells grow into the structure that is printed and develop into a fully functional organ. It is an additive manufacturing technology that has gained popularity and interest in the last few decades. Three-dimensional bioprinting has led to a remarkable advancement in the health sector, especially in regenerative medicine. There is a scarcity of available organs globally that are needed for rehabilitating lost or failed organs and tissues. Regenerative medicine is the branch of medicine that helps regrow and repair cells and organs that are deceased and damaged by either trauma or some congenital issues. Regenerative medicine includes generating tissues and organs by using therapeutic stem cells that facilitate the on-demand printing of tissues, cells, and organs. These technological advancements have led to the foundation of a new scientific field of medicine called “tissue engineering”.
Next Generation Tissue Engineering Strategies by Combination of Organoid Formation and 3D Bioprinting
Published in Naznin Sultana, Sanchita Bandyopadhyay-Ghosh, Chin Fhong Soon, Tissue Engineering Strategies for Organ Regeneration, 2020
Shikha Chawla, Juhi Chakraborty, Sourabh Ghosh
The final goal of 3D bioprinting is the design and development of functional anatomically relevant human tissues/organs to replace the diseased, damaged tissues/organs, to develop person-specific, defect-site specific constructs. Nevertheless, there are many unsolved challenges to resolve. For example, development of fully vascularized 3D bioprinted structures with anatomically relevant thickness and rigidity to ensure integration with the native tissue post-implantation is still a challenge. No studies till date could recapitulate complex anatomical architecture of kidney, liver, cardiac tissues. In such scenario, combination of organoid development strategies combined with 3D bioprinting and developmental biology inspired in vitro approaches might be an answer to prepare “organ germ” for organ replacement.
The decay of Six Sigma and the rise of Quality 4.0 in manufacturing innovation
Published in Quality Engineering, 2023
Carlos A. Escobar, Daniela Macias-Arregoyta, Ruben Morales-Menendez
Additive manufacturing drives major innovations. For instance, recent advances in the field have enabled the 3D printing of biocompatible materials, cells, and supporting components in complex functional living tissues. 3D bioprinting involves additional complexities and technical challenges related to the sensitivity of living cells and tissue construction. Therefore, addressing these complexities requires the integration of technologies from various fields, including AI. 3D bioprinting has already been used for the generation and transplantation of various tissues, including multilayer skin, bone, vascular grafts, tracheal splints, cardiac tissue, and cartilaginous structures (Murphy and Atala 2014).
Application of multi-criteria decision-making methods in the selection of additive manufacturing materials for solid ankle foot orthoses
Published in Journal of Engineering Design, 2023
Muhammad Abas, Tufail Habib, Sahar Noor, Dominik Zimon, Joanna Woźniak
Additive manufacturing (AM) is a process that constructs three-dimensional parts directly from computer-aided design (CAD) models by adding and fusing layers of material. In the medical industry, AM finds many applications, ranging from the production of surgical instruments, visual models, and hearing aids or preparing drugs in tailored doses for patients (Priyadarshini et al. 2023). Notably, significant advancements have been made in 3D bioprinting, where living cells are used to create tissues or organs through a 3D printing process (Pahlevanzadeh et al. 2020).
Advanced processing of 3D printed biocomposite materials using artificial intelligence
Published in Materials and Manufacturing Processes, 2022
Deepak Verma, Yu Dong, Mohit Sharma, Arun Kumar Chaudhary
In 2020, 3D printing enabled to manufacture parts by utilizing advanced materials such as rigid or flexible plastics. Bio-based materials tend to be more popular along with nylon 11 materials used in 3D printing. 3D bioprinting is of particular interest in the medical field for distinct applications such as organ transplant, prosthetics, and tissue engineering etc.[35]