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Efficacy and safety assessment of an ultrasound-based thermal treatment of varicose veins in a sheep model
Published in International Journal of Hyperthermia, 2020
Nesrine Barnat, Anthony Grisey, Bjoern Gerold, Sylvain Yon, Jérémie Anquez, Jean-François Aubry
Treatments of varicose veins aim at eliminating the pathologic vein from the venous circulation. This can be achieved by surgical removal of the vein or, less invasively, by chemical (sclerotherapy) or thermal occlusion of the vein. The two most frequently used thermal procedures include endovenous laser treatment (EVLT) [4] and radiofrequency ablation (RFA) [5]. They both consist in introducing an optical fiber or a catheter into the target vein and heating the vein to cause vein wall collagen contraction, endothelium destruction, vein wall inflammatory reaction and finally fibrosis [6]. Laser-based interventions have been reported to be better tolerated than RF [7]. The long-term goal of these thermal treatments is to induce complete shrinking or to occlude the pathologic vein.