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Chromosome Pairing and Fertility in Mice
Published in Christopher B. Gillies, Fertility and Chromosome Pairing: Recent Studies in Plants and Animals, 2020
Pairing between the sex chromosomes is almost normal in X-A translocations, especially when the breakpoint in the X chromosome is proximal (T37H, T38H, T2R1, and T3R1). Y univalents (the II + I + I configurations of Table 5) also are hardly found in T1R1, T5R1, and T6R1, which is remarkable because of the shortness of the translocated X segment. There are even indications of a more persistent synapsis of the Y in these situations.44,45 Another observation of Ashley pertains to nonhomologous synapsis in heteromorphic bivalents, which is more frequently encountered when nonhomologous synapsis also occurs in the quadrivalents. Thus, X and autosomal material can be nonhomologously synapsed.45Pertinent to the purpose of this chapter is what connections can be drawn between the pairing behavior thus observed, the pachytene stages at which they occur, and the subsequent fate of the pachytene spermatocytes. Unfortunately, no attempt at meiotic staging has been undertaken. Neither histological data nor testes weights of these X-A translocations has been supplied.
Chemosensation
Published in Emily Crews Splane, Neil E. Rowland, Anaya Mitra, Psychology of Eating, 2019
Emily Crews Splane, Neil E. Rowland, Anaya Mitra
Umami may also have multiple mechanisms for transduction, although the best known is again a heterodimer, this time T1R1 and T1R3. Thus, there is some similarity in the receptor class and mechanism for umami taste. There is some evidence these dimers respond best to a mixture of monosodium glutamate and nucleotides such as inosine monophosphate.
A comparison expression analysis of CXCR4, CXCL9 and Caspase-9 in dermal vascular endothelial cells between keloids and normal skin on chemotaxis and apoptosis
Published in Journal of Plastic Surgery and Hand Surgery, 2022
Xinhang Dong, Mingzi Zhang, Yuanjing Chen, Chengcheng Li, Youbin Wang, Xiaolei Jin
We examined and verified the expression of CXCR4, CXCL9, Caspase-9, ADCY1, APLN, GRM2, APLNR, GALR2, TAS1R1 and NPY2R in keloids and normal skin tissues by RT-qPCR. The mRNA expression levels of the selected genes in the Keloid group were significantly higher, compared with the Normal skin group, respectively (Figure 5).