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COVID-19 Pandemic and Traditional Chinese Medicines
Published in Hanadi Talal Ahmedah, Muhammad Riaz, Sagheer Ahmed, Marius Alexandru Moga, The Covid-19 Pandemic, 2023
Roheena Abdullah, Ayesha Toor, Hina Qaiser, Afshan Kaleem, Mehwish Iqtedar, Tehreema Iftikhar, Muhammad Riaz, Dou Deqiang
Xiyanping injection is involved in curing cough, detoxification, soothing away fever and dysentery. Clinically Xiyanping injection is used in TCM for treating bacterial diseases, bronchitis, and tonsillitis [21]. Xiyanping injection contains Andrographis Herba [34]. Andrographolide compound is the active compound of the herb in xiyanping injection that acts as antipyretic and anti-inflammatory. A diterpene bicycle ring and a γ lactone ring together form andrographolide and the structural double bonds determine the anti-inflammatory activity of the injection. An experiment involving treatment of various influenza viruses by administering andrographolide compound proved that its activity could reduce inflammatory cytokine expression, reduce viral load, lessen viral load, lessen pathological changes in lungs, inhibit apoptosis and increase survival rate of infected [21].
Comparative efficacy and safety of antiviral traditional Chinese medicine injections for viral pneumonia: a systematic review and network meta-analysis
Published in Expert Review of Anti-infective Therapy, 2022
Meng-Ting Li, Jia Wang, Jia Hu, Han-Biao Wu, Wei-Shang Deng, Zhi-Kun Qiu, Ji-Sheng Chen
Inclusion and exclusion criteria were developed according to PICOS principles. Inclusion criteria are listed as follows: (1)Participants: Patients with VP diagnosed according to international or local diagnostic criteria were included [5]. (2) Intervention: Eight of TCMIs (Xiyanping injection = XYP, Reduning injection = RDN, Tanreqing injection = TRQ, Xuebijing injection = XBJ, Yanhuning injection = YHN, Chuanhuning injection = CHN, Shuanghuanglian injection = SHL, and Qingkailing injection = QKL) along with conventional antiviral drugs (CAD) was taken in the treatment group. Based on these, patients could receive relevant therapy if they had complications during the therapeutic process. (3) Comparison: Only the same CAD as the treatment group was taken in the control group. (4) Outcomes: The primary outcomes were clinical efficacy and the rate of adverse events. The secondary outcomes were time to lung rales disappearing, time to cough subsided, time to fever resolution, time to cough relief, the length of hospital stay, and time to the disappearance of dyspnea. (5) Study: Only randomized controlled trials (RCTs).