China
Africa
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Traditional Medicinal Plants for Respiratory Diseases: Mexico
Published in Megh R. Goyal, Durgesh Nandini Chauhan, Assessment of Medicinal Plants for Human Health, 2020
Armando Enrique González-Stuart, José O. Rivera
The genus Datura contains various species that are hallucinogenic and have been used for centuries in magic and healing rituals.57 The medicinal and hallucinogenic uses of toloache were banned by the Mexican government many years ago, owing to the potential toxicity of its internal use. The plant contains various tropane alkaloids (including scopolamine and hyoscyamine), found in other species of the nightshade family, to which it belongs. For many decades, D. stramonium was included in the pharmacopeias of Mexico, the United States, as well as many other countries in America and Europe. Various respiratory diseases, especially asthma, have been traditionally treated using this plant by means of various preparations including powders and cigarettes made from the leaves. The tropane alkaloids do indeed have bronchodilating effect, but are not safe to use, especially in children.58
Restricted and Banned Herbals
Published in Amritpal Singh Saroya, Reverse Pharmacology, 2018
Botany:D. stramonium is an erect, annual, growing up to 60 to 150 cm. The root is long, thick, fibrous and white. The stem is erect, smooth and pale yellow-green in colour. The stem forks off repeatedly into branches. Each fork forms a leaf and a single, erect flower. The leaves are, smooth, toothed, and undulated.
Catalog of Herbs
Published in James A. Duke, Handbook of Medicinal Herbs, 2018
Mostly considered a noxious weed, stramonium has few legitimate uses outside the drug trade. The seeds are so toxic as to have been used in suicides and homicides; the victim experiences dry throat, giddiness, hallucination, staggering; his voice becomes unrecognizable and the vision is affected; he lapses into coma which may be terminal. Still, gamblers are said to have nibbled on the seeds for clairvoyance. Sexual functions are said to be excited, more especially in women, in whom it may cause nymphomania.19 Perhaps this led Rose to publish her recipe for a stramonium douche adding “it could be dangerous.”47 Atropine, a strategic drug in the U.S., can be obtained from jimsonweed. It is mydriatic, antisialogogue, and depresses the muscles of the bladder, thereby controlling urination. It is also used (in China) for flatulence, hyperacidity, and nightsweats of tuberculosis.16
Datura and Brugmansia plants related antimuscarinic toxicity: an analysis of poisoning cases reported to the Taiwan poison control center
Published in Clinical Toxicology, 2019
Uyen Vy Doan, Ming-Ling Wu, Dong-Haur Phua, Bomar Mendez Rojas, Chen-Chang Yang
Datura and Brugmansia poisonings are reported in the literature but the causes of poisoning are different across continents and countries. Most cases of Datura poisoning in the United States are due to Datura stramonium seeds and are mainly attributed to recreational use in young adults and adolescents. The reported percentage of intentional misuse or abuse varied between 78.3% and 94.5% [1–4]. By contrast, the reason for reports of Datura poisoning was more diverse in European countries and had included various accidents such as touching flowers, cleaning the garden, misidentification of plants, robbery, and use of the plant in traditional medicine. Moreover, the incriminated plant species were not limited to D. stramonium, but also included D. inoxia, Brugmansia suaveolens (previously known as Datura suaveolens), and B. aborea [5–11].
A comparative study of stability, antioxidant, DNA cleavage and antibacterial activities of green and chemically synthesized silver nanoparticles
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2018
Mohammad Mousavi-Khattat, Mehrnaz Keyhanfar, Amir Razmjou
The D. stramonium seeds were purchased from Pakan bazr co (Isfahan, Iran) and cultured in separated pots at greenhouse of University of Isfahan. Harvesting the leaves was done after three months when the grown plants were in the flowering stage having the maximum amount of phytochemicals [38]. The leaves were cut and washed three times by double distilled water and dried completely at room temperature. Two grams of powdered dry leaves were mixed by 100 ml double distilled water, heated for 20 min at 80 °C and filtered through Whatman No.1 filter paper. The extract solution was dehydrated and scraped to obtain a dry extract. One gram of the dried extract was dissolved in 99 ml of double distilled water and pH was adjusted to make a one wt % extract solution. Then, the solution was heated at 50 °C for 10 min under vigorous stirring to complete dissolving of the dried extract.
A comprehensive review of cardiotoxic effects of selected plants
Published in Toxin Reviews, 2021
Akbar Anaeigoudari, Nahid Azdaki, Mohammad Reza Khazdair
Datura stramonium (D. stramonium) is an annual, leafy plant (Figure 2), that grows along roadsides in the urban and rural areas. All parts of the plant contain tropane alkaloids such as atropine, hyoscyamine which are toxic. Poisoning with this plant can occur after consuming any part of the plant (Dugan et al.1989). The major constituents in seed oil of D. stramonium including; citral (26.5%), 4,8-dimethyl-3,8-dien-2-one (11.2%), sesquirosefuran (11.1%) and geraniol (10.5%) were identified by gas chromatography-mass spectrometry (GC-MS) (Aboluwodi et al.2017).