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Breast Thermography
Published in James Stewart Campbell, M. Nathaniel Mead, Human Medical Thermography, 2023
James Stewart Campbell, M. Nathaniel Mead
“Alternative” medical treatments are not always safe or benign. The thermographer may encounter patients who have self-treated palpable breast masses with escharotic salves, on the theory that chemically burning the overlying skin will “dissolve” the underlying mass. These salves often contain bloodroot (Sanguinaria canadensis) or other topically toxic ingredients. If used over a period of time, escharotics kill the dermis, leaving a full-thickness denuded wound that appears very warm to thermal imaging (Figure 9.30). This inflamed wound obscures any thermal findings from the underlying mass, making breast thermography useless until the area heals completely. Ultrasonography, X-ray mammography, or breast MRI may be required to determine the nature of any masses.
The Early Middle Ages
Published in Scott M. Jackson, Skin Disease and the History of Dermatology, 2023
In the Lacnunga, there is guidance on how to remedy carbuncles, lice (including a concoction applied thrice to the navel), itching, warty eruptions, black ulcers, erysipelas, and wens (infected follicle). For the latter, For a wen salve, take helenium and radish and chervil and ravens foot, English rape and fennel and sage, and southernwood, and pound them together, and take a good deal of garlic, pound and wring these through a cloth into spoilt honey: when it is thoroughly sodden, then add pepper and zedoary and galingale and ginger and cinnamon and laurel berries and pyrethrum, a good deal of each according to its efficacy: and when the juice of the worts and honey are so mingled, then seethe thou it twice as strongly as it was before sodden; then wilt thou have a good salve against wens.58
Monographs of fragrance chemicals and extracts that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
A woman presented with a 2-month history of perioral eczema mainly on the upper lip. The lips were edematous and erythematous, with peripheral scaling outside the vermilion border. Patch tests were carried out with the standard series, a dentist series, face and cosmetics series and one product used by the patient. Despite previous positive results, these were all negative. Biopsy of the oral mucosa of the upper lip showed histological features of contact dermatitis. At review, the patient mentioned her long-term use of a strawberry-flavored lip salve, with soothing extract of camomile. A patch test with this product was positive. Patch tests to the individual constituents of the lip salve were positive to the strawberry flavor 1% pet., but not to the others. Patch tests were subsequently carried out to the individual constituents of the flavor and a positive reaction was observed to maltol 1% pet.; 30 controls were negative to the same preparation. The use of the lip salve was stopped and the cheilitis resolved within a few days. It has not recurred in the following 12 months (1).
Prevention and treatment of burn wound infections: the role of topical antimicrobials
Published in Expert Review of Anti-infective Therapy, 2022
Deepak K. Ozhathil, Steven E. Wolf
Over the last century, outcomes in burn injury management have improved substantially. Though credit for this success is multifactorial, topical antimicrobial therapies have had an undeniable impact on reducing mortality for the most severely injured patients. Over time, however, as paradigms in surgical management have shifted, so has the role of topical antimicrobial therapies. During the eras of non-operative management and expectant management, antimicrobial salves were the primary therapy for burn wound management. In the era of early excision and wound closure, antibiotic ointments and irrigations were used as adjuncts to surgical therapy. Now as we enter the era of minimally invasive surgery, antimicrobial dressings have gained prominence for their utility as both operative adjuncts and non-operative treatments. Unfortunately, high quality comparative literature is limited to guide optimal use for many of these products.
Antimicrobial properties of rosin acids-loaded nanoparticles against antibiotic-sensitive and antibiotic-resistant foodborne pathogens
Published in Artificial Cells, Nanomedicine, and Biotechnology, 2018
Elisa Santovito, José das Neves, Donato Greco, Vito D’Ascanio, Bruno Sarmento, Antonio Francesco Logrieco, Giuseppina Avantaggiato
Coniferous trees secrete resin at the sites of mechanical injury to prevent the invasion of pathogenic bacteria and fungi, and to deter herbivorous animals. Rosin acids (RA) are mainly extracted from the resin of Pinus species. The purified resin (rosin) contains hydrophobic diterpene carboxylic acids, mainly abietic, dehydroabietic, neoabietic, isopimaric, levopimaric and palustric acids [1]. A number of in vitro tests demonstrated their efficacy as antimicrobials against a broad spectrum of microbes [2–4]. In clinical trials, rosin-based salves have been proven to enhance the healing of skin infections associated with wounds and ulcers [5,6]. Although the antimicrobial mechanism of action of RA have not been completely elucidated, whereas transmission and scanning electron microscopy and electron physiology studies showed that the exposure of Staphylococcus aureus to rosin affected wall thickness, cell aggregation, fatty acids structure and membrane potential [7]. As a result, the membrane loses its integrity leading to structural and functional disruptions that affect the energy metabolism and cell viability [7,8].
Black salve treatment of skin cancer: a review
Published in Journal of Dermatological Treatment, 2018
More recently, salve preparations have made a return as treatment of various skin ailments. Despite advancements in conventional treatment modalities for skin cancer, there is a growing trend of patients seeking alternative therapies, fueled by easy access to information on the Internet. This has led to multiple outlets selling black salve as a cure for skin cancer based on anecdotal data. This is a review of the published literature to date on the use of black salve to treat skin cancer.