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Ethnobotany of the Silk Road – Georgia, the Cradle of Wine
Published in Raymond Cooper, Jeffrey John Deakin, Natural Products of Silk Road Plants, 2020
Rainer W. Bussmann, Narel Y. Paniagua Zambrana, Shalva Sikharulidze, Zaal Kikvidze, David Kikodze, David Tchelidze, Ketevan Batsatsashvili
Even more surprising is the wide variety of young leaves of wild vegetables, which are consumed as food in the Spring (Figure 11.9), e.g., Atriplex hortensis L., Berberis vulgaris L. (fruits), Campanula lactiflora M. Bieb., Cirsium arvense (L.) Scop., Dryopteris filx-mas (L.) Schott., Fritillaria collina Adams, Lamium album L., Lathyrus roseus Steven, Lilium ledbourii (Baker) Boiss., Malva neglecta Wall and Malva sylvestris L., Mattheuccia struthiopteris (L.) Todd., Myosotis arvensis (L.) Hill, Oberna lacera (Steven) Ikonn. and O. wallichiana (Klotzsch) Ikonn., Petasites albus (L.) Gaertn and Petasites hybridus (L.) G. Gaertn., Polygonatum glaberrimum C. Koch. and Polygonatum orientale Desf., Polygonum alpinum All.; Polygonum aviculare L.; Polygonum carneum C. Koch; Polygonum. hydropiper L., Portulacca oleracea L., Primula woronowii Losinsk., Rubia tinctoria L., Rumex acetosa L.; Rumex acetosella L.; Rumex. confertus Willd.; Rumex conglomeratus Murray; Rumex crispus L.; Rumex tuberosus L.; Smilax excelsa L., Stellaria media (L.) Vill., Viola arvensis L., and finally, Viola odorata L.
Inhibiting Insulin Resistance and Accumulation of Triglycerides and Cholesterol in the Liver
Published in Christophe Wiart, Medicinal Plants in Asia for Metabolic Syndrome, 2017
Synonyms: Convallaria odorata Mill.; Polygonatum japonicum C. Morren & Decne.; Polygonatum maximowiczii F. Schmidt; Polygonatum officinale All; Polygonatum vulgare Desf.Common name: yu zhu (Chinese)Subclass Liliidae, Superorder Lilianae, Order Asparagales, Family AsparagaceaeMedicinal use: cough (China)Pharmacological target: insulin resistance
Ashtavarga Plants: A Review
Published in T. Pullaiah, K. V. Krishnamurthy, Bir Bahadur, Ethnobotany of India, 2017
S. John Adams, T. Senthil Kumar, G. Muthuraman, Anju Majeed
Polygonatum cirrhifolium (Family: Liliaceae) is commonly called “Mahameda.” It is also a tall erect, perennial herb, 60-120 cm high with whorled (3-6) sessile, linear leaves having tendril-like tips. Flowers white, green purplish or pink on short stocks and the fruit is round blue-black berry. The plant is found in the temperate Himalayas (Garhwal, Gulabkoti, Sitapur, Sutul and Khirsu) at altitudes of 1200-4200 m (Naithani 1984; Gaur 1999). The fleshy and thick rhizome have a cooling, and mild laxative, effect, it is also a galactagogue, aphrodisiac, depurative, febrifuge, expectorant and tonic. It heals wound. Compounds extracted from its rhizome exhibit fungicidal activities. P. cirrhifolium is reported to be used as a tonic and vulnerary. A root infusion with milk is used as an aphrodisiac and as a blood purifier for tumors and piles. Investigations in China have reported hypoglycemic, hypotensive, antibacterial and antifungal effects. Its ayurvedic dynamics are: sweet in taste, cold in potency, pacifies vata and pitta (Singh, 2006). Rhizome shows actinocytic stomata in the lower leaf epidermis, cortex with the polygonal to isodiametric cells, scattered amphivasal vascular bundles, numerous starch grains and presence of both raphides and druses in idioblastic cavities. Powder shows simple and compound ovoid, concentric starch grains (Anonymous, 2011). The important chemicals of this plant are given in Table 6.2.
JianPi-QingHua formula attenuates nonalcoholic fatty liver disease by regulating the AMPK/SIRT1/NF-κB pathway in high-fat-diet-fed C57BL/6 mice
Published in Pharmaceutical Biology, 2023
Jing Tian, Mengjie Cai, Shenyi Jin, Qingguang Chen, Jiahui Xu, Qiuyue Guo, Zihui Yan, Xu Han, Hao Lu
Jianpi-Qinghua Formula (JPQH), which was derived from ‘Bupiwei Xieyinhuo Shengyang Decoction’, was proposed by Shuguang Hospital Affiliated with Shanghai University of Traditional Chinese Medicine (Shanghai, China) (Liu et al. 2022). The compositions of JPQH included Codonopsis pilosula (Franch.) Nannf (Campanulaceae), Astragalus membranaceus (Fisch.) Bunge (Leguminosae), Dioscorea opposita Thunb. (Dioscoreceae), Polygonatum sibiricum Red. (Liliaceae), Coptis chinensis Franch. (Ranunculaceae), Scutellaria baicalensis Georgi (Lamiaceae Martinov), Pueraria Lobata (Willd.) Ohwi. (Leguminosae) and Euonymus alatus (Thunb.) Sieb (Celastraceae). This formula has been used for more than two decades, and it is known for the treatment of lipid metabolism, intestinal inflammation, obesity, and insulin resistance (Gong et al. 2020; Liu et al. 2022). Our past study found that puerarin inhibited the hepatic gluconeogenesis via activation of PI3K/Akt pathway in diabetic rats (Liu et al. 2021). However, its therapeutic mechanism in the treatment of NAFLD has been unclear. Therefore, our study investigates whether JPQH will attenuate HFD-induced NAFLD by regulating hepatic lipid metabolism and inflammation.
Mechanochemical prepared ibuprofen-Polygonatum sibiricum polysaccharide drug delivery system for enhanced bioactivity with reduced renal injury induced by NSAIDs
Published in Drug Delivery, 2022
Wenhao Xu, Jinli Yang, Xiangyang Gu, Wenjing Su, Faxiang Pu, Zhangfu Xie, Kongliang Jin, Weike Su, Lichan Mao
Ibuprofen (purity 98%) was purchased from Aladdin Biotechnology Co., Ltd. (Xian, China). Polygonatum sibiricum Red. were collected in April 2020 in Chizhou, Anhui, China, and were identified by Dr. Yi Tao from Zhejiang University of Technology. (+)-Arabinogalactan (AG) from Larch Wood (purity 99%, CAS 9036-66-2) was purchased from Beijing Budweiser Technology Co., Ltd. (Beijing, China). Carrageenan (purity 98%, CAS 9000-07-1) was purchased from Aladdin Biotechnology Co., Ltd. (Xian, China). The XOD and ADA assay kits were produced by Nanjing Jiancheng Biotech (Nanjing, China). Malondialdehyde (MDA), superoxide dismutase (SOD), TUNEL kits, and uric acid (UA), creatinine (Cr), blood urea nitrogen (BUN), and adenosine deaminase (ADA) assay kits were from Beyotime Biotechnology (Haimen, China). All other chemicals used were of analytical grade.
Polygonatum sibiricum polysaccharide inhibits high glucose-induced oxidative stress, inflammatory response, and apoptosis in RPE cells
Published in Journal of Receptors and Signal Transduction, 2022
Wenjun Wang, Shang Li, Meixia Song
Traditional Chinese medicine (TCM) has been widely used for a long time and is regarded as the most important therapeutic in China [13]. Polygonatum sibiricum polysaccharides (PSP) are a group important component of Polygonatum sibiricum (PS), which is well known as a traditional medicinal herb and functional food and has been introduced in the 2015 edition of pharmacopeia [14]. PSP have been found to possess many pharmacological applications and biological activities, such as anti-oxidative, anti-aging, immunity regulation, anti-inflammatory, anti-cancer, and anti-diabetic effects [15–20]. However, the effect and underlying mechanism of PSP on diabetic retinopathy remains unclear. In this study, we investigated the effects of PSP on HG-induced oxidative stress and inflammation in ARPE-19 cells.