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Assyria
Published in Michael J. O’Dowd, The History of Medications for Women, 2020
Extract of Mandrake (Mandragora officinalis), known as the ‘devil plant’ and the ‘male namtar plant of the North’, was used during difficult labor. It was advised that the stomach of a woman in difficult labor should be anointed seven times with root extract. Mandrake was known to many cultures and gained further fame when eulogized by Shakespeare in Othello, Act 3, Scene 3, line 331: Nor all the drowsy syrups of the world,not poppy nor mandragora.
The advent of anaesthesia and antisepsis
Published in Harold Ellis, Sala Abdalla, A History of Surgery, 2018
From earliest times, attempts have been made to dull the pain of injuries and of surgery. Large doses of alcohol, opium or laudanum (tincture of opium and alcohol) taken by mouth, or mandragora (obtained from the mandrake plant, Mandragora officinarum, which contains hyoscine and other alkaloid drugs), were used. Much effort was expended on the psychological preparation of the patient before surgery, and some good effects could be obtained by hypnotism, since its introduction as ‘mesmerism’ by Anton Mesmer (1734–1815).
M
Published in Anton Sebastian, A Dictionary of the History of Medicine, 2018
Mandrake Also known as Mandragora root, in the family Solanaceae. Ancient herbal remedy and an important ingredient in philters used by ancient sorcerers. Its root is said to resemble the human form. Theophrastus called it ‘anthropomorphos’ for this reason. Shakespeare refers to the root in at least four plays. The Babylonians and Hebrews were familiar with it and a wine was used in surgery by Dioscorides (AD 40–90) during the time of Nero. Aulus Cornelius Celsus, who wrote De Medicina, mentioned use of mandrake and poppy for relief of pain.
Contributions of Avicenna to surgery and anesthesiology
Published in Acta Chirurgica Belgica, 2020
In case it is alluring to get an individual rapidly oblivious, without hurting him, add sweet smelling moss to the wine, or Aquilaria sinensis. If a deeply unconscious state is desirable, then add an infusion of Lolium persicum into the wine, or administer Fumaria officinalis, Papaver somniferum and Hyoscyamus niger [half dram dose or 1.84 ml of each]; Myristica fragrans and Aquilaria sinensis [4 grain or 0.25 g of each]. Add this to the wine, andgive as much as is needed. Or on the other hand boil Hyoscyamus niger in water, with Mandragora officinarum bark until it becomes red. Add this to the wine [18].
Phytodermatitis in East and southeast of Turkey: A prospective study
Published in Cutaneous and Ocular Toxicology, 2019
Mandragora species belonging to Solanaceae family have sedative, aphrodisiac, analgesic, and anesthetic properties25. Mandragora species include alkaloids such as mandragorine, hyoscyamine, scopolamine, apoatropine, and atropine5. The cases of poisoning caused by the systemic use of M. autumnalis have been reported26. In addition, a case of ICD in the knee due to topical application of M. autumnalis has been reported in our region2. In our study, ICD developed in the knees of a patient due to topical application of M. autumnalis (Figure 8).