Combination reaction

Nutrition for health and sports performance

Published in Nick Draper, Helen Marshall, Exercise Physiology, 2014

As suggested by its name, a synthesis (or combination) reaction involves bond formation between atoms and/or molecules to form larger, more complex molecules. The formation of water from hydrogen and oxygen molecules is an example of a synthesis reaction. A simple synthesis reaction can be represented as:

Anti-tuberculosis drug delivery for tuberculous bone defects

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Journal Information

Published in Expert Opinion on Drug Delivery, 2021

Long Hua, Hu Qian, Ting Lei, Wenbin Liu, Xi He, Yu Zhang, Pengfei Lei, Yihe Hu

Mesoporous bioactive glass (MBG) is composed of silicon, sodium, calcium, and phosphorus oxides. Its ingredients are bionic that produce hydroxyl calcium phosphate after the combination reaction. This ingredient is a component of human and animal bones, and has good biological activity. Therefore, MBG has a promising application in tissue engineering scaffolds, orthopedics, dentistry, and drug carriers [84]. Xu et al. [10] used 30 mg/ml INH and RFP dual-drug loading, explored the cytocompatibility and cytotoxicity, and found that the material had good cytocompatibility and low biotoxicity. The doping of MBG and hydrogel increased the compressive strength of the material. Zhu et al. [40] loaded INH and RFP onto PHBHHx and doped it with MBG, and the compressive strength reached 3.15 ± 0.69 MPa. MBG can also load NIV and provide a slow-release time. Hlaka et al. [85] loaded minor groove binders through MBG, and the drug was still detected on day 12. These results indicate that MBG, as a drug carrier, has sustained release and mechanical properties.

Combination reaction

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