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Monographs of fragrance chemicals and extracts that have caused contact allergy / allergic contact dermatitis
Published in Anton C. de Groot, Monographs in Contact Allergy, 2021
Results of studies patch testing alpha-pinene in groups of selected patients (e.g. patients allergic to turpentine oil, individuals allergic to tea tree oil) are shown in table 3.139.2. In five investigations, high frequencies of sensitization to alpha-pinene were observed, ranging from 50% to 77% (1,9,11,12,13). This is the result of selection of patients allergic to turpentine oil, in which alpha-pinene is one of the main allergens, and in some types the most frequent one (Chapter 6.75 Turpentine oil). The fact that 4 out of 7 (57%) of patients allergic to tea tree oil in a German study also reacted to alpha-pinene (1) is more difficult to explain, as this chemical is not an important allergen in tea tree oil (Chapter 6.71 Tea tree oil). Possibly, these tea tree oil-allergic patients had previously also become sensitized to turpentine oil, an allergy which is very common in Germany.
Fluorescence in Phytopreparations
Published in Victoria Vladimirovna Roshchina, Fluorescence of Living Plant Cells for Phytomedicine Preparations, 2020
Victoria Vladimirovna Roshchina
Juniper (Juniperus communis) berry essential oil (JEO) is traditionally used for flavoring and medicinal purposes. It also known as the common juniper, is a dioecious aromatic evergreen shrub, and has been traditionally used in many countries as a diuretic, antiseptic, and digestive and as a flavor to aromatize certain alcoholic beverages (Falasca et al. 2016). A total of 90 components have been detected, and among them, remarkable qualitative and quantitative differences have been observed in the chemical components during the ripening stages, from the green unripe berries to the bluish-black berries harvested at full maturity. The monoterpene hydrocarbons decrease during ripening, with a progressive increase in sesquiterpenes such as germacrene D (12.29–17.59%) and β-caryophyllene (7.71–8.51%), which are the major components in ripe berry essential oils. This oil and its major active component alpha-pinene have been studied for antimicrobial, antifungal, antiproliferative, anti-inflammatory, and anticancer activities in a variety of settings (Bais et al. 2014). Admixture may include flavons (Bais et al. 2016). In addition, it has gained increasing popularity for skin health purposes. However, a literature search conducted by us showed no published studies regarding biological activity in human skin cells.
Insight into Knapsack Metabolite Ecology Database: A Comprehensive Source of Species: Voc-Biological Activity Relationships
Published in Raquel Cumeras, Xavier Correig, Volatile organic compound analysis in biomedical diagnosis applications, 2018
Azian Azamimi Abdullah, M.D. Altaf-Ul-Amin, Shigehiko Kanaya
To understand the relationships between VOCs and their biological activities, we also integrate the KNApSAcK Metabolite Ecology Database with KNApSAcK Metabolite Activity Database. Information on biological activities of VOCs can be obtained by clicking the ‘A’ button in Figure Figure 9.3B. Figure 9.5 shows the search result of biological activities related to C_ID C00000805, which was retrieved from the KNApSAcK Metabolite Activity Database. The attributes in the list are C_ID, metabolite name, activity category, biological activity, target species and references, from left to right. Here, the metabolite known as alpha-pinene (C_ID C00000805) has several biological activities such as antimicrobial, antioxidant, biomarker, defense, enhance plant growth, anticholinesterase, and antifungal.
Loading, release profile and accelerated stability assessment of monoterpenes-loaded solid lipid nanoparticles (SLN)
Published in Pharmaceutical Development and Technology, 2020
Aleksandra Zielińska, Nuno R. Ferreira, Agnieszka Feliczak-Guzik, Izabela Nowak, Eliana B. Souto
The calibration curves for each of analyzed monoterpenes dissolved in PBS were determined at the distinctive wavelength for each of monoterpenes. Alpha-pinene were analyzed by UV assay at 230 nm, against the calibration curve y = 0.0031x + 0.01307, citral at 280 nm against the calibration curve y = 0.0056x + 0.0249, geraniol at 290 nm against the calibration curve y = 0.0022x + 0.0094, and limonene at 290 nm against the calibration curve y = 0.0096x + 0.0166.