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Role of Onion (Allium cepa) in Gastrointestinal Disorders
Published in Megh R. Goyal, Preeti Birwal, Durgesh Nandini Chauhan, Herbs, Spices, and Medicinal Plants for Human Gastrointestinal Disorders, 2023
Yaw Duah Boakye, Richard Agyen, Eugene Kusi Agyei, Daniel Obeng Mensah, Doreen Kwankyewaa Adjei, Christian Agyare
Onion is known to contain quercetin, flavonoid, trace minerals, and chromium,27,29 but saponins, quercetin, and anthocyanin are the primary phytochemicals. They contain sulfur compounds, such as allyl-propyl-disulfide that gives the pungent smell.22,37 S-propenylcysteine sulfoxide (major component), S-methylcysteine sulfoxide, S-propylcysteine sulfoxide, and dipropyl disulfide are organosulfur compounds, which are found in onion.13,43
Cyanides, sulfides, and carbon monoxide
Published in Bev-Lorraine True, Robert H. Dreisbach, Dreisbach’s HANDBOOK of POISONING, 2001
Bev-Lorraine True, Robert H. Dreisbach
Ethylmercaptan, methylmercaptan, and other mercaptans in high concentrations cause cyanosis, convulsions, hemolytic anemia, fever, coma, and irreversible depression of cerebral function. Perchloromethyl-mercaptan is a severe pulmonary irritant. Allyl propyl disulfide (onion oil) is a mild pulmonary and mucous membrane irritant.
Effect of Steamed Onion (ONIRO) Consumption on Body Fat and Metabolic Profiles in Overweight Subjects: A 12-Week Randomized, Double-Blind, Placebo-Controlled Clinical Trial
Published in Journal of the American College of Nutrition, 2020
Sarang Jeong, Jisuk Chae, Gahyun Lee, Gurum Shin, Young-In Kwon, Jung-Bae Oh, Dong Yeob Shin, Jong Ho Lee
Onion is an important dietary source that contains bioactive flavonoids, including quercetin, quercitrin, and rutin (16), and sulfur-containing compounds, mainly allyl propyl disulfide and diallyl disulfide (17). These compounds are known to have health benefits including antioxidant, antidiabetic, anti-inflammatory, hypotensive, and hypocholesterolemic properties and other various biological actions (18,19). In particular, onion extract was reported to have antiobesity effects by reducing visceral adipose tissue through inhibition of preadipocyte differentiation and adipogenesis in rat model (20,21). Furthermore, Lee et al. (22) have reported that quercetin-rich onion peel extract supplementation reduced the body weight and percentage of body fat in overweight and obese subjects as measured by dual-energy x-ray absorptiometry (DEXA). It has also been reported that supplementation with onion peel extract has favorably modulated serum lipid profiles such as plasma TG, low-density lipoprotein (LDL) cholesterol, and cholesterol level in healthy young individuals (23). Likewise, supplementation with quercetin, a major bioactive flavonoid, or quercetin-rich onion extract was shown to be effective in improving blood lipid profiles and in prevention of obesity in both humans and rats (24–26). Despite promising findings, the efficacy of these supplementations seems to be dependent on several indices, such as dosage, duration, and processing of onion extract.